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CellAura To Develop Reagents For Tag-lite[TM] GPCR Technology Platform for Cisbio Bioassays.


Fluorescence fluorescence (flrĕs`əns), luminescence in which light of a visible color is emitted from a substance under stimulation or excitation by light or other forms of electromagnetic  reagents provide key non-radioactive choice

NOTTINGHAM, England -- CellAura, the leading producer of fluorescence reagents for drug discovery and life sciences research, today announced a development partnership with Cisbio Bioassays. Under the terms of the agreement, CellAura will provide pharmacologically validated reagents to Cisbio Bioassays that will be applied to Cisbio Bioassays' Tag-lite[TM] range of non-radioactive assays for cellular studies.

Commenting on the collaboration, CellAura CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  Dai Hayward said: "Maximising cellular information is increasingly seen as the key to successful drug discovery. CellAura combines world-renowned expertise from the University of Nottingham The University of Nottingham is a leading research and teaching university in the city of Nottingham, in the East Midlands of England. It is a member of the Russell Group, and of Universitas 21, an international network of research-led universities.  in the fields of synthetic chemistry and molecular pharmacology pharmacology, study of the changes produced in living animals by chemical substances, especially the actions of drugs, substances used to treat disease. Systematic investigation of the effects of drugs based on animal experimentation and the use of isolated and  to produce high quality fluorescent receptor ligands as key components in drug candidate screening assays and imaging techniques. This new partnership with Cisbio Bioassays, which is one of the leaders in bioassays for cell surface receptor and functional studies, recognizes our rapid progress and is a major milestone."

CellAura will develop a number of reagents for Cisbio Bioassays' Tag-lite[TM] range. Tag-lite, part of Cisbio Bioassays' comprehensive HTRF HTRF Homogenous Time-Resolved Fluorescence
HTRF Heat Transfer Research Facility
 cellular platform, provides a homogeneous, non-radioactive and cost-effective alternative for the study of cell surface receptor dimerization and ligand ligand (lĭg`ənd), charged or uncharged molecule with one or more unshared pairs of electrons that can attach to a central metallic atom or ion to form an aggregate known as a complex ion (see chemical bond).  binding.

Fran[?]ois Degorce, head of marketing for Cisbio Bioassays added: "GPCR GPCR Guanine Nucleotide-Binding Protein-Coupled Receptor
GPCR GTP-binding Protein-Coupled Receptor
 and more generally cell surface receptor investigation are currently among the hottest topics in drug discovery. To enhance our Tag-lite platform addressing this area, we seek out partnerships with the best experts in their respective fields, and are pleased to collaborate with CellAura for the development of non-radioactive fluorescent ligands."

CellAura will also retain rights for the reagents developed for use in their own range of assays for certain markets. Financial details were not disclosed.

For more information visit www.cellaura.com
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Comment:CellAura To Develop Reagents For Tag-lite[TM] GPCR Technology Platform for Cisbio Bioassays.
Publication:Business Wire
Geographic Code:4EUUE
Date:Oct 22, 2009
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