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Cell-skeleton changes linked to cancer?

Cell-skeleton changes linked to cancer?

Mutations in a gene coding for the most abundant structuralprotein in cells may lead to cancer, say researchers at Stanford University and the Linus Pauling Institute of Science and Medicine in Palo Alto, Calif. The discovery of the gene, which directs production of beta-actin protein, adds a new twist to the expanding list of genes thought responsible for cancer. Prior to the current studies, these so-called oncogenes were thought to change the protein growth factors of a cell, not its interior framework. But, as reported in the July MOLECULAR AND CELLULAR BIOLOGY, the researchers were able to change normal cells to cancerous cells by injecting mutant beta-actin genes.
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Publication:Science News
Date:Aug 1, 1987
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