Carnipure suppresses bone turnover.A new study released by the University of Connecticut The University of Connecticut is the State of Connecticut's land-grant university. It was founded in 1881 and serves more than 27,000 students on its six campuses, including more than 9,000 graduate students in multiple programs. UConn's main campus is in Storrs, Connecticut. and published in Phytomedicim suggests supplementation with Carnipure, which is manufactured by Lonza, can slow bone loss and improve bone mierostructural properties by decreasing bone turnover in aged ovariectomized: rats. For this trial, ovariectomized female rats were assigned to two different groups--one received a diet without L-carnitine supplementation and the other received the same diet plus Carnipure during a 5-week period. Different dietary treatments did not significantly affect food intake or body weight, although there was a tendency of lower body weight in the Carnipure supplemented group. Mean tibial tibial pertaining to the tibia. tibial crest a longitudinal prominence on the cranial border of the proximal tibia. Its proximal end (tibial tubercle) has a growth plate separate from the proximal tibia; hyperflexion injuries to bone mineral density bone mineral density n. See bone density. bone mineral density A measurement of bone mass, expressed as the amount of mineral–in grams divided by the area scanned in cm2. See Bone densitometry. of the Carnipure supplemented rats was significantly higher, over 6% compared to the control group. This is considered clinically relevant when comparing the results with certain approved medications for osteoporosis. Carnipure supplementation was also found to decrease gene expressions of TRAP, a measure of bone resorption Bone resorption is the process by which osteoclasts break down bone and release the minerals, resulting in a transfer of calcium from bone fluid to the blood. The osteoclasts are multi-nucleated cells that contain numerous mitochondria and lysosomes. , by nearly 73% while also decreasing two markers of bone formation by over 60%, compared with the control group. According to according to prep. 1. As stated or indicated by; on the authority of: according to historians. 2. In keeping with: according to instructions. 3. these findings, researchers believe Carnipure supplementation can suppress the rate of bone turnover. For further information: 201-316-9413. |
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