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Cardiva Medical, Inc. to Present at Medtech Insight and Windhover Information's ``Investment In Innovation (In3) WEST'' Conference, February 23-24, 2006, Irvine, CA.


MOUNTAIN VIEW, Calif. -- Evolutionary Percutaneous percutaneous /per·cu·ta·ne·ous/ (per?ku-ta´ne-us) performed through the skin.

per·cu·ta·ne·ous
adj.
Passed, done, or effected through the unbroken skin.
 Access Management Device is Safe, Easy to Use and Improves Manual Compression Efficiency

Cardiva Medical, Inc., a privately held medical device company, announced that it will be presenting at 9:30 A.M. on February 24 at Medtech Insight and Windhover wind·hov·er  
n. Chiefly British
A kestrel.
 Information's "Investment In Innovation (In3) WEST: A Preview of Early-Stage Medical Technology Companies" Conference, February 23-24, 2006 at the Hyatt Regency Irvine in Irvine, California Irvine is an incorporated city in Orange County, California, United States. It is a planned city, mainly developed by the Irvine Company since the 1960s. Formally incorporated on December 28 1971, the 69.7 square mile (180.5 km²) city has a population of 202,079 (as of 2007). . Cardiva Medical, Inc. ("The Company") received clearance from the U.S. Food and Drug Administration ("FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
") to market the Boomerang(TM) Percutaneous Access Management System ("Boomerang (TM)") in November 2004. The Boomerang(TM) Wire is cleared to assist clinicians in closing femoral artery femoral artery
n.
1. An artery with origin at the continuation of the external iliac artery, with branches to the pudendal, epigastric, circumflex iliac arteries, the deep artery of the thigh, and the descending genicular artery, and
 punctures sites following the most common percutaneous procedures, such as diagnostic angiography angiography
 or arteriography

X-ray examination of arteries and veins with a contrast medium to differentiate them from surrounding organs. The contrast medium is introduced through a catheter to show the blood vessels and the structures they supply, including
, angioplasty angioplasty (ăn`jēōplăs'tē), any surgical repair of a blood vessel, especially

balloon angioplasty or percutaneous transluminal coronary angioplasty, a treatment of coronary artery disease.
, and stenting. The Company has been actively marketing the Boomerang(TM) device through its direct sales force and has seen tremendous success in the market since its product launch about a year ago.

Millions of percutaneous catheterizations are performed world-wide each year, with approximately 80% of such procedures being diagnostic angiography. During percutaneous catheterization catheterization

Threading of a flexible tube (catheter) through a channel in the body to inject drugs or a contrast medium, measure and record flow and pressures, inspect structures, take samples, diagnose disorders, or clear blockages.
 procedures, the catheter is threaded through the femoral artery to the site of vascular disease (most common is in the heart), where diagnosis and/or treatment (such as stenting or angioplasty), can be performed. Traditionally, doctors have used various methods to close the femoral artery puncture site, including direct manual or mechanical compression over the femoral femoral /fem·o·ral/ (fem´or-al) pertaining to the femur or to the thigh.

fem·o·ral
adj.
Of or relating to the femur or thigh.
 puncture site or one of the implantable vascular closure devices, which use various biomaterials (such as collagen, gels, sutures, or staples) to create a physical seal of the femoral artery puncture site.

Direct manual compression can be quite painful for the patient and may require several hours of bed-rest to achieve complete hemostasis hemostasis /he·mo·sta·sis/ (he?mo-sta´sis) (he-mos´tah-sis)
1. the arrest of bleeding by the physiological properties of vasoconstriction and coagulation or by surgical means.

2.
; while implantable vascular closure devices achieve hemostasis in minutes, but have been associated with catastrophic complications. Cardiva's Boomerang(TM) is designed to improve manual compression efficiency and to leave nothing behind in the femoral artery or at the puncture site, thereby avoiding the implantable closure device related complications.

Since the market clearance by the FDA in late 2004, more than 10,000 patients have been treated with the Boomerang(TM) device following percutaneous procedures. Clinical results from this large pool of post-market patients have demonstrated the excellent efficacy and safety, with virtually no major complications, of using the Boomerang(TM) device.

In practice, at the end of the percutaneous procedure, the Boomerang(TM) device is inserted into the artery through the existing arterial sheath used during the catheterization procedure. Upon removal of arterial sheath, the Boomerang(TM) disc is positioned against the opening of the femoral artery for a tight seal and immediate hemostasis in the cath lab A catheterization laboratory or cath lab is an examination room in a hospital or clinic with diagnostic imaging equipment to support the catheterization procedure. A catheter is inserted into a large artery, and various wires and devices can be inserted through the body via . Once the patient arrives into the recovery room, the Boomerang(TM) disc is collapsed and the device is completely removed from the artery, leaving nothing behind in the tissue tract or artery following the Boomerang(TM) procedure, with final hemostasis achieved with a few minutes of manual compression.

Augustine Y. Lien, founder, Chairman and Chief Executive Officer of Cardiva, said, "We believe that the Boomerang(TM) device is not only far more comfortable and cost-effective for patients undergoing manual compression of the femoral artery opening, but also provides unsurpassed safety for patients and ease-of-use for medical practitioners when compared to existing implantable vascular closure devices. We are pleased and encouraged by rapid adoption of this new technology by the clinicians as the clinical and cost benefits of the Boomerang(TM) are becoming more obvious in their practices and more important to their patients."

A division of Windhover Information Inc., Medtech Insight is the leading provider of business information and market intelligence for the medical technology marketplace. In3 WEST is Medtech Insight's 20th investment and partnering event to date. To register to attend or for more information on Medtech Insight, please call Kristy Grimes Grimes is a surname, that is believed to be of a Scandinavian decent and may refer to
  • Aoibhinn Grimes
  • Ashley Grimes
  • Barbara Grimes, a Chicago murder victim
  • Burleigh Grimes (1893–1985), US baseball player
  • Camryn Grimes
  • Charles Grimes
 at (480) 985-9512 or (888) 202-5939 toll-free in the U.S., e-mail kristy@medtechinsight.com, or visit www.medtechinsight.com.
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Publication:Business Wire
Date:Feb 17, 2006
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