CardioVascular BioTherapeutics to Present at Euro-Biotech Forum.LAS VEGAS -- CardioVascular BioTherapeutics, Inc. (OTCBB OTCBB See OTC Bulletin Board (OTCBB). :CVBT CVBT Cardiovascular Biotherapeutics, Inc CVBT Central Virginia Battlefields Trust (Fredericksburg, VA Civil War history organization) ) today announced that it will present a session on protein angiogenesis for the treatment of cardiovascular disease at the Euro-Biotech Forum, taking place in Paris from June 26-28, 2007. The presentation, titled "New Progress in Protein Angiogenesis Therapy for Cardiovascular Disease Patients," will be given by Dr. Jack Jacobs, vice president and chief operating officer Chief Operating Officer (COO) The officer of a firm responsible for day-to-day management, usually the president or an executive vice-president. of CVBT. This presentation will provide a look at the developing field of protein therapy for the treatment of cardiovascular disease, which is the number one killer of adults worldwide. The medical industry is in serious need of new treatment options for the many diseases encompassed by cardiovascular disease, including peripheral artery disease, coronary heart disease coronary heart disease: see coronary artery disease. coronary heart disease or ischemic heart disease Progressive reduction of blood supply to the heart muscle due to narrowing or blocking of a coronary artery (see atherosclerosis). , stroke and wound healing disorders associated with diabetes. CVBT is developing a protein-based technology by which a member of the human Fibroblast Growth Factor Fibroblast growth factors, or FGFs, are a family of growth factors involved in wound healing and embryonic development. The FGFs are heparin-binding proteins and interactions with cell-surface associated heparan sulfate proteoglycans have been shown to be essential for FGF family, known as Fibroblast fibroblast /fi·bro·blast/ (fi´bro-blast) 1. an immature fiber-producing cell of connective tissue capable of differentiating into chondroblast, collagenoblast, or osteoblast. 2. Growth Factor-1 (FGF-1), stimulates angiogenesis, or new blood vessel growth. Research and previous clinical trials have shown the protein can stimulate new blood vessel growth approximately two months after injection into several types of tissues that suffer from poor blood perfusion due to blockage of arteries. FGF-1 is a natural product found in the human body. The use of its angiogenic potency represents a new approach to treating a disease that is devastating both to patients and the healthcare industry given the economic burden of treating the disease. "Cardiovascular disease is the underlying cause of more than one third of the deaths in the United States. Nearly 2,400 Americans die of cardiovascular disease each day, an average of one death every 36 seconds, and it is clear that there is an opportunity and a dire need to improve the treatment of this disease," said Dr. Jacobs. "The American Heart Association American Heart Association (AHA), n.pr a national voluntary health agency that has the goal of increasing public and medical awareness of cardiovascular diseases and stroke, and thereby reducing the number of associated deaths and disabilities. estimates that the cost of cardiovascular diseases and stroke in the United States alone for 2007 will be $431.8 billion. This figure includes hospital costs, medical professional services and drug costs. Through scientific innovation, CVBT has developed and is committed to bringing to market a cost-effective drug candidate that will reduce the suffering and improve the quality of life of individuals affected by this disease." The 14th Annual Euro-Biotech Forum is a partnering meeting for American and European life science companies offering company presentations, meetings and networking functions designed to bring together the brightest ideas in the biotech industry. The event is a forum for thought leaders to engage in debates, present case studies and share best practices for the development of cutting-edge biotechnology products. About CardioVascular BioTherapeutics CVBT is a biopharmaceutical company developing formulations of Fibroblast Growth Factor-1 (FGF-1) to treat a number of diseases characterized by inadequate blood flow to a tissue or organ. The Company is developing injectable and topical formulations of FGF-1 to facilitate angiogenesis in the heart, organs and other tissues. Enrollment and treatment has been completed in an FDA-authorized Phase I study with FGF-1 administered in patients with severe Coronary Heart Disease. A Phase II trial in a similar patient population is under FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. review and is planned to start this year. Additionally, CVBT is close to completion of a Phase I clinical trial Noun 1. phase I clinical trial - a clinical trial on a few persons to determine the safety of a new drug or invasive medical device; for drugs, dosage or toxicity limits should be obtained phase I for dermal dermal /der·mal/ (der´mal) pertaining to the dermis or to the skin. der·mal or der·mic adj. Of or relating to the skin or dermis. diabetic and venous ulcer healing, where its drug candidate CVBT-141B (containing FGF-1) was applied topically. CVBT also has initiated a Phase I clinical trial using a third drug candidate, CVBT-141C, in patients with Peripheral Arterial Disease. |
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