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Cappella Inc. to Present at Medtech Insight and Windhover Information's ``In3 Medical Device Summit'' Conference, June 21-23, 2006 in San Francisco, CA.


SAN FRANCISCO -- Cappella Inc. has announced that it will be presenting on June 22nd, 2006 at 15:40 at Medtech Insight and Windhover wind·hov·er  
n. Chiefly British
A kestrel.
 Information's "In3 Medical Device Summit" Conference, June 21-23, 2006 at The Palace Hotel in San Francisco, CA.

In3 attendees will get a chance to see firsthand the next generation in bifurcation Bifurcation

A term used in finance that refers to a splitting of something into two separate pieces.

Notes:
Generally, this term is used to refer to the splitting of a security into two separate pieces for the purpose of complex taxation advantages.
 stenting.

According to Guy Neev, Vice President of Marketing & Business Development, "Our protection device is poised to become the gold standard in the treatment of bifurcation and ostial lesions."

Cappella Inc. has developed both a drug delivery device and technique for approaching and treating patients with ostial-bifurcation lesions. The Sideguard ostium ostium /os·ti·um/ (os´te-um) pl. os´tia   [L.] an opening or orifice.os´tial

ostium abdomina´le tu´bae uteri´nae
 protection device is a self-expanding coronary drug-eluting stent technology that is deployed into the sidebranch first.

The Sideguard's trumpet-shaped design helps the stent conform to the ostium, allowing for complete stent-to-wall apposition apposition /ap·po·si·tion/ (ap?o-zish´un) juxtaposition; the placing of things in proximity; specifically, the deposition of successive layers upon those already present, as in cell walls.  and continuous drug delivery. This alleviates many of the problems associated with deploying multiple stents simultaneously, yet leaves the parent and side-branch free for future stenting.

"What makes Sideguard different than conventional DES or dedicated bifurcation stent technologies is Sideguard's concept and design," states Neev. Sideguard will be the first commercialized dedicated side-branch stent with a built-in circumferential ostium support feature.

Professor Donald Baim, who recently presented his experience in the animal lab with Cappella, stated that "IVUS IVUS Intravascular ultrasound, see there , radiography radiography: see X ray.  and histology show excellent expansion in both the side-branch and the main vessel, full lumenal patency pa·ten·cy
n.
The state or quality of being open, expanded, or unblocked.



patency

the condition of being open.
, and complete wall apposition through the ostial transition segment. This should translate into uniform drug-delivery and low clinical restenosis rates."

"Our stent is the first nitinol balloon-released, sheathed coronary stent coronary stent Intracoronary stent Cardiology An expandable tubular device which can be inserted percutaneously, and left within a coronary artery lumen to maintain its patency Pros Clinical and angiographic outcomes are better with intracoronary artery stent . Using nitinol (a memory metal) allows us to pre-shape the stent before crimping it to the delivery system. Then, a protective sheath is applied to keep it in place until deployment. Once it's released, it expands into place and its pre-shaped trumpet design allows the stent to hug to the vessel wall and ostium, providing complete apposition and continuous drug delivery," points out Guy Neev.

According to Professor Campbell Rogers, a Sideguard principal investigator, the Sideguard's ease of delivery, favorable acute angiographic results (as reported in animal studies), and its seamless apposition (as demonstrated by both IVUS and histology) make Sideguard a potential alternative to current bifurcation stent practices and make it an appealing platform for drug delivery.

Cappella is an emerging technologies company specializing in the development, manufacturing, and commercialization of coronary stents and stent delivery technologies. Founded in 2004 by Professor Antonio Colombo & Dr. Ascher Shmulewitz, Cappella will offer the interventional cardiology interventional cardiology Cardiology The subspecialty of cardiology dedicated to the diagnosis, medical and mechanical therapy, pre- and post-procedure management of adult patients with acute and chronic forms of cardiovascular disease amenable to catheter-based  community a more deliverable and effective stent alternative specifically designed for the treatment of bifurcated bi·fur·cate  
v. bi·fur·cat·ed, bi·fur·cat·ing, bi·fur·cates

v.tr.
To divide into two parts or branches.

v.intr.
To separate into two parts or branches; fork.

adj.
 & ostial lesions.

A division of Windhover Information Inc., Medtech Insight is the leading provider of business information and market intelligence for the medical technology marketplace. The In3 Medical Device Summit (www.meddevicesummit.com) is Medtech Insight's 21st investment and partnering event to date. To register to attend or for more information on Medtech Insight, please call Kristy Grimes at (480) 985-9512 or (888) 202-5939 toll-free in the U.S., e-mail kristy@medtechinsight.com, or visit www.medtechinsight.com.
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Date:Jun 12, 2006
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