Capillary/micro HPLC. (Instruments).

The continuing trend towards micro and capillary HPLC is said to have hastened the development of a specialist detector for such separations. A microbore evaporative light scattering (ELS) detector, the PL-ELS 1000[micro], has been specifically designed for optimized performance in microbore and capillary HPLC applications. The PL-ELS 1000[micro] is said to provide unrivalled baseline stability for HPLC separations requiting gradient elution. The detector operates with eluent flow rates from 1 [micro]l/min, to 500 [micro]l/min. The PL-ELS 1000[micro] detector can detect all non-volatile solutes, there is no dependence on a UV chromophore and it is designed for minimal band broadening. The use of microbore and now capillary columns permits lower detection limits compared to conventional HPLC columns, which, when coupled with the increased sensitivity of the PL-ELS 1000[micro], provides a system capable of significant reductions in solute limits of detection. This ELS detector is said to be ideal as a stand-alone detector for separations using capillaries down to 300 [micro]m ID, and/or can be used as a split flow concentration detector in conjunction with LC-MS systems. (Polymer Laboratories)

Circle 107 on card