Canadian scientists decode DNA of breast cancer tumor.Toronto, Oct 8 (ANI): For the first time, scientists have decoded the entire genome of a patient's metastatic Metastatic The term used to describe a secondary cancer, or one that has spread from one area of the body to another. Mentioned in: Coagulation Disorders metastatic pertaining to or of the nature of a metastasis. breast cancer-a breakthrough towards creating personalized per·son·al·ize tr.v. per·son·al·ized, per·son·al·iz·ing, per·son·al·iz·es 1. To take (a general remark or characterization) in a personal manner. 2. To attribute human or personal qualities to; personify. cancer therapies using a patient's genetic information. The achievement could change how people think about the way cancer develops and provides new insights into which drugs could benefit patients the most. "I'm excited by the possibilities. In fact, I never thought I would see in my professional lifetime that it would become possible to routinely sequence genomes in the way that we're now doing," The Globe and Mail quoted Samuel Aparicio, the head of the department of breast and molecular oncology at the B.C. Cancer Agency and one of the lead scientists involved with the discovery, as saying. While decoding de·code tr.v. de·cod·ed, de·cod·ing, de·codes 1. To convert from code into plain text. 2. To convert from a scrambled electronic signal into an interpretable one. 3. the metastatic breast-cancer genome, which contains all of the genetic information of a patient's cancer, scientists could identify all of the mutations in the tumour- a feat that has never before been accomplished. After identifying all of the tumour mutations of the developed cancer - a total of 32 were found - scientists had the information to look back and see which of those mutations were present in the patient's original, primary tumour. They discovered that only 11 of the 32 mutations were present in the original tumour, with only five of those present in all of the original cancer cells cells once believed to be peculiar to cancers, but now know to be epithelial cells differing in no respect from those found elsewhere in the body, and distinguished only by peculiarity of location and grouping. See also: Cancer , which means that even in the early stages, cancer cells aren't uniform. This proves that even from the outset, cancer cells contain different mutations, which change over time. "I think we're getting used to the idea an individual patient's cancer is itself multiple individual cancers that may behave differently," said Aparicio. Aparicio said their work could help usher in Verb 1. usher in - be a precursor of; "The fall of the Berlin Wall ushered in the post-Cold War period" inaugurate, introduce commence, lead off, start, begin - set in motion, cause to start; "The U.S. a new era in which scientists will be able to decode (1) To convert coded data back into its original form. Contrast with encode. (2) Same as decrypt. See cryptography. (cryptography) decode - To apply decryption. cancer genomes in all patients to help create therapies targeted to the mutations present in their tumours. The findings of the study are published in the journal Nature. (ANI) Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency. (ANI) - All Rights Reserved. Provided by Syndigate.info an Albawaba.com company |
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