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Can sunscreen nanoparticles cause Alzheimer's disease?


Byline: ANI

London, Aug 25 (ANI): Researchers at University of Ulster The University of Ulster (UU; Irish: Ollscoil Uladh[2] [3]) is a multi-centre university located in Northern Ireland and is the largest single university on the island of Ireland, discounting the federal  are all set to probe whether some man-made nanoparticles, such as those found in sunscreens Sunscreens Definition

Sunscreens are products applied to the skin to protect against the harmful effects of the sun's ultraviolet (UV) rays.
Purpose

Everyone needs a little sunshine.
, are linked with Alzheimer's disease Alzheimer's disease (ăls`hī'mərz, ôls–), degenerative disease of nerve cells in the cerebral cortex that leads to atrophy of the brain and senile dementia. .

Led by professor Vyvyan Howard and Dr Christian Holscher at the Biomedical Sciences Institute in Coleraine, the research will look into whether engineered nanoparticles can induce neurodegenerative disease Neurodegenerative disease
A disease in which the nervous system progressively and irreversibly deteriorates.

Mentioned in: Amnesia
.

Howard said that they would examine whether there was a significant risk associated with such nanoparticles.

"The overall science and technology objective of this programme is to determine if engineered nanoparticles could constitute a significant neuro-toxicological risk to humans for two diseases - Alzheimer's and Parkinson's," the BBC BBC
 in full British Broadcasting Corp.

Publicly financed broadcasting system in Britain. A private company at its founding in 1922, it was replaced by a public corporation under royal charter in 1927.
 quoted him as saying.

The experts will be looking at nanoparticles present in chemicals found in sunscreens and an additive in some diesel fuels - titanium dioxide and cerium cerium (sēr`ēəm) [from the asteroid Ceres], metallic chemical element; symbol Ce; at. no. 58; at. wt. 140.12; m.p. 799°C;; b.p. 3,426°C;; sp. gr. 6.77 at 25°C;; valence +3 or +4.  oxide - and their connection to Alzheimer's and Parkinson's diseases.

"There is now firm evidence that some engineered nanoparticles entering intravenously or via lungs can reach the brains of small animals. Indeed they lodge in almost all parts of the brain and there are no efficient clearance mechanisms to remove them once there," said Howard.

"There are also suggestions that nanoscale particles arising from urban pollution have reached the brains of animals and children living in Mexico City.

"It has recently been discovered that nanoparticles can have highly significant impacts on the rate of misfolding of key proteins associated with neurodegenerative diseases neurodegenerative diseases

diseases characterized by neurodegeneration. Lesions are microscopic only but in chronic disease with massive involvement there may be grossly visible atrophy of affected nervous tissue.
 like Alzheimer's and Parkinson's disease.

"The brain itself is a very special organ. It cannot repair by replacing nerve cells, the ones you get at birth have to last all your life, which makes them peculiarly vulnerable to long term low dose toxicity," he added.

Dr. Susanne Sorensen, head of research at the Alzheimer's Society, said: "We do not advise people to stop using sunscreen as it has been proven to reduce your risk of developing skin cancer however we welcome research into the long term safety of modern products.

"There is currently no research data directly linking the use of sun screen to development of Alzheimer's disease," she added. (ANI)

Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency.  (ANI) - All Rights Reserved.

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Publication:Asian News International
Date:Aug 25, 2009
Words:363
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