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Caloric test findings in a patient with recurrent disequilibrium. (Vestibulology Clinic).


A 38-year-old man first came to the office with a complaint of two episodes of dizziness. The first, which had occurred 2 years earlier, was characterized by a lack of balance while walking or standing. He also reported a lightheaded component to his symptoms. He was prescribed lorazepam lorazepam /lor·a·ze·pam/ (lor-az´e-pam) a benzodiazepine used as an antianxiety agent, sedative-hypnotic, preanesthetic medication, and anticonvulsant.

lor·az·e·pam
n.
, which provided some mild benefit. Findings on magnetic resonance imaging magnetic resonance imaging (MRI), noninvasive diagnostic technique that uses nuclear magnetic resonance to produce cross-sectional images of organs and other internal body structures.  were negative. His dizziness persisted for 6 weeks, then disappeared.

The second episode had occurred 2 weeks prior to his first office visit. The patient had noticed the dizziness upon awakening. Once he was out of bed, he noted a problem with his balance and a feeling of lightheadedness. He was restarted on lorazepam but, again, the benefit was minimal. His symptoms were most intense when he was standing and walking; they were not present when he was lying down, and they were only minor when he was seated and moving his head. Although his dizziness was not severe, it was intrusive and distracting. The patient had no subjective hearing loss, tinnitus, or aural fullness. His family history was positive for hearing loss and tinnitus. He performed the sharpened tandem Romberg's test with difficulty.

The patient went on vacation, and when he returned to the office for testing, he reported that his symptoms had disappeared while he had been away, only to recur to a lesser degree when he returned to work. While under the effects of lorazepam and hydroxyzine HCl (for chronic pruritus pruritus /pru·ri·tus/ (proo-ri´tus) itching.prurit´ic

pruritus a´ni  intense chronic itching in the anal region.

pruritus hiema´lis  xerotic eczema.
), the patient underwent electronystagmography, which revealed no spontaneous or positional nystagmus. Alternate binaural binaural /bi·nau·ral/ (bi-naw´r'l) pertaining to both ears.

bin·au·ral
adj.
Having or relating to both ears.



binaural

pertaining to both ears.
 bithermal testing elicited hyperactive responses (>25[degrees]/sec) to the cool stimulus in both ears and to the warm stimulus in the left ear. According to Jongkees' formula, the patient had no reduced vestibular response or directional preponderance (DP). Simultaneous binaural bithermal testing yielded a type 3 response with a left-beating nystagmus Nystagmus Definition

Rhythmic, oscillating motions of the eyes are called nystagmus. The to-and-fro motion is generally involuntary. Vertical nystagmus occurs much less frequently than horizontal nystagmus and is often, but not necessarily, a sign of
. A type 3 response defines DP and is abnormal. Some of these findings, especially the hyperactive responses to caloric stimulation, might have reflected the effects of his drug therapy. Nevertheless, combined with his history, they suggested the presence of a peripheral vestibular disorder peripheral vestibular disorder Neurology A hallucination of movement, either subjective or objective History Duration of an attack–eg, hrs v. days, frequency daily v. .

From Neurotologic Associates, P.C., New York City New York City: see New York, city.
New York City

City (pop., 2000: 8,008,278), southeastern New York, at the mouth of the Hudson River. The largest city in the U.S.
.
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Author:Brookler, Kenneth H.
Publication:Ear, Nose and Throat Journal
Geographic Code:1USA
Date:Dec 1, 2002
Words:358
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