CRF Inc. e-Diary Technology Use Tops 150,000 Patients Worldwide; Company continues to set experience records for the electronic patient reported outcomes industry.

WALTHAM, Mass. -- CRF Inc., the world leader in electronic Patient Reported Outcomes (e-PRO) and wireless data collection solutions for the biopharmaceutical industry, today announced that its mobile technology has connected more than 150,000 patients across 58 countries and in 57 languages. This milestone sets a new industry experience standard and continues CRF Inc.'s record-setting pace, which began when the company became the first e-PRO provider to reach 50,000 patients in February 2004.

"This accomplishment is the result of CRF's tireless work to provide the most accessible and user-friendly ePRO solution on the market," said Pamela McNamara, Chief Executive Officer of CRF Inc. "We continue to set the standard for quality in patient reported outcomes with a compliance rate of 95 percent and have enhanced our technology to overcome the traditional barriers of language, culture and geography. Our TrialMax(TM) technology has become a critical tool for the biopharmaceutical industry to be ahead of the critical path, by increasing accuracy and reliability of data while simplifying the long and expensive trial process."

CRF celebrates another year of achievement, both within the company and through its customers' effective and efficient use of its products.

--New Languages: With the addition of Arabic, Hebrew and Thai, the TrialMax system can now be operated in a total of 57 different languages;

--Cost Savings for Companies: CRF customers continue to perform successful and financially rewarding trials. A global pharmaceutical company used CRF Inc.'s TrialMax(TM) to manage a clinical trial for a Rotavirus vaccination. The trial involved remote monitoring and analysis of more than 15,000 pediatric patients across three countries whose parents/caregivers used TrialMax(TM)-enabled cell phones to report safety and symptom data. The sponsor reported that CRF Inc.'s technology radically reduced follow up costs associated with the trial, resulting in a cost savings of approximately $2.7 million compared with traditional paper diaries;(1)

--Successful Trials: Another leading pharmaceutical company used TrialMax(TM)-equipped PDAs to collect data on statininteraction rates from 20,000 patients at 100 sites across Europe. As a result, the company's market share increase with ROI was 400 percent;(2)

--New Staff: CRF has also recently strengthened its management team. In his role as Chief Technology Officer, Pekka Keskiivari will oversee ongoing development of CRF's award winning product, TrialMax,(TM) and will nurture, support, and manage technological innovation throughout CRF. Rachael King has joined the company as Customer Delivery Operations Leader for Europe. Her extensive experience in the development of electronic patient diaries and management of operations that deliver these services will enhance eDiary development.

About CRF Inc.

CRF Inc. is the leading global provider of electronic Patient Reported Outcomes (e-PRO) and wireless data collection solutions for the biopharmaceutical industry. Through innovative technology and a thorough understanding of drug development and mobile computing, the company is driving the change to safer and more efficient paper-free clinical trials. CRF Inc.'s technology has been used by more than 150,000 patients across 58 countries in 57 languages for more than 40 indications. The company has demonstrated the industry's highest patient compliance rates -- an average 95 percent compliance through Phase I, II, III and IV clinical trials -- and unmatched patient and research site acceptance.

CRF Inc.'s award-winning product, TrialMax 3.2, is a flexible and customizable e-PRO technology that provides real-time patient monitoring, outstanding data accuracy and increased safety. Its unique features enable clinical trial sponsors to collect more valuable data faster and conduct complex clinical trials with greater flexibility than other e-PRO solutions. CRF Inc.'s experience combined with its dedication to ensuring the highest quality and most responsive customer service has made the company the biopharmaceutical industry's most trusted partner.

For more information, please visit www.crfhealth.com.

(1) Data on file, CRF Inc. - http://www.crfhealth.com/case_histories.html

(2) Data on file, CRF Inc. - http://www.crfhealth.com/case_histories.html