CME questions: arthritis.1. All of the following biologic agents modulate tumor necrosis factor-mediated processes EXCEPT: a. Infliximab b. Rituximab c. Adalimumab d. Etanercept 2. Which of the following is considered a standard first-line therapy for the treatment of fibromyalgia fibromyalgia Chronic syndrome that is characterized by musculoskeletal pain, often at multiple sites. The cause is unknown. A significant number of persons with fibromyalgia also have mental disorders, especially depression. ? a. Methotrexate methotrexate, drug used in halting the growth of actively proliferating tissues. Introduced in the 1950s, it is used in the treatment of leukemia, psoriasis, and non-Hodgkin's lymphoma. b. Corticosteroids Corticosteroids Definition Corticosteroids are group of natural and synthetic analogues of the hormones secreted by the hypothalamic-anterior pituitary-adrenocortical (HPA) axis, more commonly referred to as the pituitary gland. c. Antidepressant antidepressant, any of a wide range of drugs used to treat psychic depression. They are given to elevate mood, counter suicidal thoughts, and increase the effectiveness of psychotherapy. medications d. Narcotic analgesics Analgesics Definition Analgesics are medicines that relieve pain. Purpose Analgesics are those drugs that mainly provide pain relief. 3. The presence of which of the following lab tests is highly specific for rheumatoid arthritis? a. Cyclic citrullinated protein antibodies b. Rheumatoid factor c. Antinuclear antibody d. Double-stranded DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. antibodies 4. Which of the following statements regarding fibromyalgia is true? a. Laboratory studies demonstrate an active inflammatory process b. Sleep disturbance is a common finding c. Presence of an inflammatory disease precludes the diagnosis of fibromyalgia in a patient d. The vast majority of patients are female 5. Which of the following are risk factors for the development of osteoarthritis osteoarthritis or osteoarthrosis or degenerative joint disease Most common joint disorder, afflicting over 80% of those who reach age 70. It does not involve excessive inflammation and may have no symptoms, especially at first. of the knee? a. Obesity b. History of exercise c. Low calcium intake 6. Indications for the use of agents directed against TNFalpha include: a. Psoriatic arthropathy arthropathy /ar·throp·a·thy/ (ahr-throp´ah-the) any joint disease.arthropath´ic Charcot's arthropathy neuropathic a. b. Rheumatoid arthritis c. Crohn disease d. All of the above 7. Presence of all the following autoantibodies are strongly associated with the diagnosis of lupus EXCEPT: a. Double-stranded DNA b. Cyclic citrullinated protein antibodies c. Smith antibodies d. Ribosomal-P-protein antibodies 8. Which of the following therapeutic modalities are not considered appropriate for fibromyalgia? a. Improving sleep quality b. Exercise program c. Disease-modifying antirheumatic therapy d. Stress-management programs 9. Potential side effects of anti-TNF therapy include which of the following: a. Increased risk of infection b. Development of autoantibodies c. Myelopathies d. All of the above 10. Which of the following is true? a. Over 15% of patients with rheumatoid arthritis are rheumatoid factor negative b. Presence of a positive antinuclear antibody indicates that the patient has lupus c. Presence of a positive rheumatoid factor is highly specific for the diagnosis of rheumatoid arthritis d. Smith antibody is present in nearly all lupus patients 1. B, 2. C, 3. A, 4. D, 5. A, 6. D, 7. B, 8. C, 9. D, 10. A |
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