CLSI Publishes New Antimicrobial Susceptibility Testing Standard.WAYNE, Pa. -- CLSI CLSI Clinical and Laboratory Standards Institute (Wayne, PA) CLSI Cisco Link Services Interface has recently published the annual update of the well-known antimicrobial susceptibility testing standard, Performance Standards for Antimicrobial Susceptibility Testing; Eighteenth Informational Supplement (M100-S18), which provides updates of the latest recommendations for detecting emerging resistance of aerobic bacteria--arranged in tabular format. The "breakpoints" included in the supplement are defined as specific values on the basis of which bacteria can be assigned to the clinical categories of susceptible, intermediate, or resistant. This essential information assists clinicians with drug selection, interpretation, and quality control using the procedures standardized in CLSI documents Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard--Ninth Edition (M2-A9); and Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard--Seventh Edition (M7-A7). This edition of the supplement includes updated tables from CLSI's disk (M2-A9) susceptibility and MIC (M7-A7) testing standards. In addition, the document provides three pages of adhesive index tabs, which can be inserted for quick access to each table. Updates include: * New column for suggested antimicrobial agents Antimicrobial agents Chemical compounds biosynthetically or synthetically produced which either destroy or usefully suppress the growth or metabolism of a variety of microscopic or submicroscopic forms of life. to be considered for other non-Enterobacteriaceae * Streptococcus streptococcus (strĕp'təkŏk`əs), any of a group of gram-positive bacteria, genus Streptococcus, some of which cause disease. spp. other than Streptococcus pneumoniae Streptococcus pneu·mo·ni·ae n. Pneumococcus. Streptococcus pneumoniae Microbiology A pathogenic streptococcus with 90 serotypes associated with pneumonia, bacteremia, meningitis Transmission Person to person Incidence separated into two columns: Streptococcus spp. beta-hemolytic group and Streptococcus spp. viridans group * New testing comment added to carbapenem box for detecting carbapenamases * Added recommendations for a broth microdilution MIC test for inducible clindamycin resistance where erythromycin erythromycin (ĭrĭth'rōmī`sĭn), any of several related antibiotic drugs produced by bacteria of the genus Streptomyces (see antibiotic). and clindamycin are tested together in a single well * Revised cefoxitin MIC interpretive criteria to predict the presence of mecA-mediated resistance in S. aureus The aureus (pl. aurei) was a gold coin of ancient Rome valued at 25 silver denarii. The aureus was regularly issued from the 1st century BC to the beginning of the 4th century AD, when it was replaced by the solidus. and S. lugdunensis * Penicillin interpretive criteria modified and separated into three categories: meningitis, nonmeningitis, and penicillin V penicillin V n. A semisynthetic oral penicillin compound that is very stable even in high humidity and that resists destruction by gastric juice. (oral) * New antimicrobial agents and QC ranges * New appendixes for screening tests For additional information on CLSI or for further information regarding this release, visit our website at http://www.clsi.org or call +610.688.0100. CLSI, formerly NCCLS NCCLS National Committee for Clinical Laboratory Standards , is a global, nonprofit, membership-based organization dedicated to developing standards and guidelines for the health care and medical testing community. CLSI's unique consensus process facilitates the creation of standards and guidelines that are reliable, practical, and achievable for an effective quality system. |
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