CLSI Publishes New Antimicrobial Susceptibility Testing Standard.WAYNE, Pa. -- CLSI CLSI Clinical and Laboratory Standards Institute (Wayne, PA)
CLSI Cisco Link Services Interface has recently published the annual update of the well-known antimicrobial susceptibility testing standard, Performance Standards for Antimicrobial Susceptibility Testing; Seventeenth Informational Supplement (M100-S17), which provides updates of the latest recommendations for detecting emerging resistance of aerobic bacteria--arranged in tabular format. The "breakpoints" included in the supplement are defined as specific values on the basis of which bacteria can be assigned to the clinical categories of susceptible, intermediate, or resistant. This essential information assists clinicians with drug selection, interpretation, and quality control using the procedures standardized in CLSI documents Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard--Ninth Edition (M2-A9); and Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard--Seventh Edition (M7-A7).
Janet F. Hindler, MCLS MCLS Metropolitan Cooperative Library System (Los Angeles, CA, USA)
MCLS Mucocutaneous Lymph Node Syndrome
MCLS Massachusetts Correctional Legal Services, Inc.
MCLS Mobilization Cross-Leveling System , MT(ASCP ASCP American Society of Clinical Pathologists. ), Senior Specialist, Clinical Microbiology Clinical microbiology
The adaptation of microbiological techniques to the study of the etiological agents of infectious disease. Clinical microbiologists determine the nature of infectious disease and test the ability of various antibiotics to inhibit or kill , UCLA Medical Center UCLA Medical Center is a hospital located on the campus of the University of California, Los Angeles in Los Angeles, California. It is rated as one of the top three hospitals in the United States and is the top hospital on the West Coast according to US News & World Report. , explains, "For over three decades, NCCLS NCCLS National Committee for Clinical Laboratory Standards and now CLSI consensus standards have been the primary resources for antimicrobial susceptibility testing in the clinical laboratory. The annual updates provide the most current recommendations to ensure accurate detection and reporting of emerging resistance."
This edition of the supplement includes updated tables from CLSI's disk (M2-A9) susceptibility and MIC (M7-A7) testing standards. In addition, the document provides three pages of adhesive index tabs, which can be inserted for quick access to each table.
* new disk diffusion and MIC interpretive criteria for colistin colistin /co·lis·tin/ (ko-lis´tin) an antibiotic produced by Bacillus polymyxa var. colistinus, related to polymyxin and effective against many gram-negative bacteria; used as the sulfate salt. and polymyxin B;
* new antimicrobial agents and QC ranges;
* preparation of stock solutions for antimicrobial agents provided with activity expressed as units;
* added information on the development of resistance and testing of repeat isolates;
* modified recommendations for testing and reporting designated clusters of agents with similar interpretive results and clinical efficacy;
* recommendations for reporting critical results; and
* suggestions for verification and confirmation of susceptibility testing results for Neisseria meningitidis Neisseria men·in·git·i·dis
The bacteria that is the causative agent of cerebrospinal meningitis; meningococcus.
Neisseria meningitidis .
For additional information on CLSI or for further information regarding this release, visit our website at http://www.clsi.org or call +610.688.0100.
CLSI is a global, nonprofit, membership-based organization dedicated to developing standards and guidelines for the healthcare and medical testing community. CLSI's unique consensus process facilitates the creation of standards and guidelines that are reliable, practical, and achievable for an effective quality system.