CEL-SCI files patent application for prevention/treatment of avian flu.CEL-SCI CORPORATION (Vienna, VA) announces that it has filed a provisional United States patent application covering its drug CEL-1000 for the prevention/treatment of bird flu bird flu: see influenza. bird flu or avian influenza viral respiratory disease, mainly of birds including poultry and waterbirds but also transmissible to humans. and/or as an adjuvant adjuvant /ad·ju·vant/ (aj?dbobr-vant) (a-joo´vant) 1. assisting or aiding. 2. a substance that aids another, such as an auxiliary remedy. 3. to be included in a bird flu vaccine. Geert Kersten, Chief Executive Officer of CEL-SCI said, "By filing this patent in the United States, we are preserving our rights to file patents on this invention world-wide." CEL-1000, when used as a single adjuvant (enhancer of a vaccine) or in combination with other adjuvants, potentiates Th1 (cellular) and innate (earliest stage) immune responses and protects animals from viral and parasitic challenge. CEL-1000 provides antigen-independent (i.e., non-disease specific) and broad-spectrum protection upon challenge with the disease causing agent(s), which is important against the bird flu virus since it exhibits a high mutation rate. CEL-1000, is a patented defined amino acid amino acid (əmē`nō), any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins. sequence derived from the beta chain of human MHC-II, which itself is a modified version of a human immune-based protein known to bind to to contract; as, to bind one's self to a wife s>. See also: Bind both human and mouse immune cells and appears to act by enhancing the host's protective immune response. It is a defined peptide, which binds to the CD4 and/or likely a related molecule LAG-3 on dendritic cells, macrophages Macrophages White blood cells whose job is to destroy invading microorganisms. Listeria monocytogenes avoids being killed and can multiply within the macrophage. and T cells, thereby promoting the release of cytokines Cytokines Chemicals made by the cells that act on other cells to stimulate or inhibit their function. Cytokines that stimulate growth are called "growth factors. responsible for activating a protective Th1 immune response (e.g., IL-12 and upon challenge IFN-gamma). CEL-SCI is developing new immune system based treatments for cancer and infectious diseases. CEL-SCI Corporation +1-703-506-9460 www.cel-sci.com |
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