CALIPER LAUNCHES NEW LABCHIP HIGH THROUGHPUT SCREENING SYSTEM.Caliper caliper
Instrument that consists of two adjustable legs or jaws for measuring the dimensions of material parts. Spring calipers have an adjusting screw and nut; firm-joint calipers use friction at the joint to hold the legs unmoving. Technologies Corp. (Nasdaq: CALP CALP Cognitive Academic Language Proficiency
CALP Cristalleria Artistica La Piana (All the World, Crystalware)
CALP Calsenilin-Like Protein
CALP Centro de Astrofísica en la Palma (Canary Islands, Spain) ) has announced the launch of the Caliper 250 HTS HTS Heights
HTS Harmonized Tariff System
HTS High Throughput Screening (biomolecular assay screening)
HTS High-Throughput Screening (Pharmaceutical Industry)
HTS Harmonized Tariff Schedule system, the company's new LabChip-based high throughput screening (HTS) system. The Caliper 250 HTS system, which includes instruments for assay development and screening, a menu of chips that perform standard assays, as well as Caliper supplied support services support services Psychology Non-health care-related ancillary services–eg, transportation, financial aid, support groups, homemaker services, respite services, and other services and custom solutions, represents a new, microfluidic chip-based approach to high throughput drug screening. Customers can purchase the new system directly from Caliper, marking the company's conversion to a full-scale commercial HTS products business.
Caliper's LabChip systems miniaturize min·i·a·tur·ize
tr.v. min·i·a·tur·ized, min·i·a·tur·iz·ing, min·i·a·tur·iz·es
To plan or make on a greatly reduced scale.
min , integrate and automate high volume screening to enable researchers to perform complex, multi-step experiments in a fraction of the time with far less user intervention, using tiny quantities of precious reagents and producing high quality, reproducible results. The Caliper 250 HTS system debuted this week at the Society for Biomolecular Screening (SBS See Small Business Server. ) 2001 Conference in Baltimore, the industry's largest forum for high throughput screening technologies. Caliper anticipates that it will begin shipping the new HTS systems in November 2001.
"Caliper's new LabChip high throughput screening system represents an important advance in our commercial strategy to be the microfluidic market leader and, for the first time, offers customers the ability to purchase HTS systems, services and custom solutions directly from Caliper's catalog catalog, descriptive list, on cards or in a book, of the contents of a library. Assurbanipal's library at Nineveh was cataloged on shelves of slate. The first known subject catalog was compiled by Callimachus at the Alexandrian Library in the 3d cent. B.C. to support their screening needs," said Dan Kisner, M.D., President and Chief Executive Officer.
"LabChip technology has the potential to bring dramatic improvements to fundamental processes of drug discovery by offering unprecedented levels of efficiency, productivity, quality and cost-savings," continued Dr. Kisner. "Caliper's LabChip HTS systems will enable screening laboratories to achieve more consistent and accurate hit and lead identification information, generate the precise, reliable, high quality information they need to make better informed decisions earlier in the discovery process and, ultimately, accelerate the process of bringing important new medicines to patients in need."
The Caliper 250 HTS system performs screening experiments in a serial, continuous flow fashion inside the microchannels of the chip, constituting a closed, controlled environment. The chip employs a proprietary capillary-like sample access system, called a "sipper," through which just nanoliters of test compounds are drawn into the channels of the chip from microwell plates. There, they are mixed with equally tiny quantities of the target biomolecule biomolecule /bio·mol·e·cule/ (-mol´e-kul) a molecule produced by living cells, e.g., a protein, carbohydrate, lipid, or nucleic acid.
a molecule produced by living cells, e.g. and other reagents for screening. The Caliper 250 HTS system uses a 4-sipper chip capable of performing tens of thousands of experiments per chip per day, depending upon assay conditions, and offers walkaway automation and minimal user intervention
Caliper is commercializing its HTS systems through its own sales and marketing force, Caliper Direct. The company is also offering a full range of customer and field support services, and a specialized spe·cial·ize
v. spe·cial·ized, spe·cial·iz·ing, spe·cial·iz·es
1. To pursue a special activity, occupation, or field of study.
2. HTS solutions program that includes specific assay development support, early access to beta products and customized microfluidic solutions for customers' individual research challenges.