CALIPER LAUNCHES NEW LABCHIP HIGH THROUGHPUT SCREENING SYSTEM.
Caliper's LabChip systems miniaturize, integrate and automate high volume screening to enable researchers to perform complex, multi-step experiments in a fraction of the time with far less user intervention, using tiny quantities of precious reagents and producing high quality, reproducible results. The Caliper 250 HTS system debuted this week at the Society for Biomolecular Screening (SBS) 2001 Conference in Baltimore, the industry's largest forum for high throughput screening technologies. Caliper anticipates that it will begin shipping the new HTS systems in November 2001.
"Caliper's new LabChip high throughput screening system represents an important advance in our commercial strategy to be the microfluidic market leader and, for the first time, offers customers the ability to purchase HTS systems, services and custom solutions directly from Caliper's catalog to support their screening needs," said Dan Kisner, M.D., President and Chief Executive Officer.
"LabChip technology has the potential to bring dramatic improvements to fundamental processes of drug discovery by offering unprecedented levels of efficiency, productivity, quality and cost-savings," continued Dr. Kisner. "Caliper's LabChip HTS systems will enable screening laboratories to achieve more consistent and accurate hit and lead identification information, generate the precise, reliable, high quality information they need to make better informed decisions earlier in the discovery process and, ultimately, accelerate the process of bringing important new medicines to patients in need."
The Caliper 250 HTS system performs screening experiments in a serial, continuous flow fashion inside the microchannels of the chip, constituting a closed, controlled environment. The chip employs a proprietary capillary-like sample access system, called a "sipper," through which just nanoliters of test compounds are drawn into the channels of the chip from microwell plates. There, they are mixed with equally tiny quantities of the target biomolecule and other reagents for screening. The Caliper 250 HTS system uses a 4-sipper chip capable of performing tens of thousands of experiments per chip per day, depending upon assay conditions, and offers walkaway automation and minimal user intervention
Caliper is commercializing its HTS systems through its own sales and marketing force, Caliper Direct. The company is also offering a full range of customer and field support services, and a specialized HTS solutions program that includes specific assay development support, early access to beta products and customized microfluidic solutions for customers' individual research challenges.