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Bruker Daltonik GmbH, PANATecs GmbH and the University of Goettingen Announce a Development Cooperation for New Molecular Diagnostic Assays for Rheumatoid Arthritis.


BREMEN, Tuebingen and GOETTINGEN, Germany -- Bruker Daltonik GmbH, the University of Goettingen and German biotech company PANATecs GmbH today announced a new development collaboration in protein biomarker discovery and molecular diagnostics research based on mass spectrometry mass spectrometry
 or mass spectroscopy

Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields.
. PANATecs will apply Bruker Daltonics' CLINPROT(TM) tools for biomarker discovery, profiling and identification in the field of rheumatoid arthritis rheumatoid arthritis

Chronic, progressive autoimmune disease causing connective-tissue inflammation, mostly in synovial joints. It can occur at any age, is more common in women, and has an unpredictable course.
 research and development.

In the joint project funded by the German Ministry of Education and Research, new tests for the molecular diagnosis of rheumatoid arthritis are expected to be developed by a combination of immunological and biochemical techniques with a mass spectrometry read-out read·out or read-out  
n. Computer Science
Presentation of data, usually in digital form, from calculations or storage.

Noun 1.
. In addition, PANATecs will offer services for biomarker identification using Bruker Daltonics' mass spectrometry equipment.

Dr. Thomas Flad, Managing Director of PANATecs, stated: "We are very pleased that Bruker Daltonics is a partner who is committed to molecular diagnostics research, and who has also the necessary depth and advanced technology in mass spectrometry to obtain high quality data from the valuable sample collections of our company and our clinical partners. The versatile sample preparation with CLINPROT beads and streamlined data interpretation with ClinProTools(TM) software, together with superior mass spectrometry technology, makes Bruker Daltonics our ideal partner in the field of biomarker analysis."

Dr. Wolfgang Pusch, Director of Clinical Proteomics and Biomarker Analysis Products of Bruker Daltonik GmbH, commented: "It is an important milestone in our efforts in clinical proteomics research that PANATecs, as a leading biotech company dedicated to developing new molecular diagnostics assays based on mass spectrometry, has made this strategic decision for our CLINPROT solution. With the high clinical capabilities of PANATecs and the Department of Nephrology nephrology

Branch of medicine dealing with kidney function and diseases. An understanding of kidney physiology is important not only in treating kidney disease but in knowing the effect of drugs, diet, and hypertension on kidney disease, and vice versa.
 and Rheumatology rheumatology /rheu·ma·tol·o·gy/ (-tol´ah-je) the branch of medicine dealing with rheumatic disorders, their causes, pathology, diagnosis, treatment, etc.

rheu·ma·tol·o·gy
n.
 at the Faculty of Medicine in Goettingen, we see a good chance for future CLINPROT molecular diagnostics of rheumatoid arthritis, or even other autoimmune diseases Autoimmune diseases
A group of diseases, like rheumatoid arthritis and systemic lupus erythematosus, in which immune cells turn on the body, attacking various tissues and organs.

Mentioned in: Complement Deficiencies, Premature Menopause
."

Prof. Dr. Gerhard Mueller, Director of the Cooperative Center for Rheumatology, University of Goettingen, concluded: "The complementary experience which the different partners contribute makes this three-party cooperation very promising. While the Center for Rheumatology will contribute the clinical expertise and access to a large number of clinically well characterized patient samples, PANATecs has significant experience concerning immunological and biochemical procedures necessary to gain access to the respective biomarker molecules. This setup is complemented by Bruker Daltonics as an advanced mass spectrometry partner with a proven commitment to clinical research."

ABOUT BRUKER BIOSCIENCES CORPORATION Bruker Biosciences Corporation is a Massachusetts-based company formed in 2003 which develops and manufactures scientific instrumentation for academic research and industrial use.  (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
: BRKR BRKR Breaker )

Bruker BioSciences Corporation, headquartered in Billerica, Massachusetts, is the publicly traded parent company of Bruker Daltonics Inc. and Bruker AXS Inc. Bruker AXS is a leading developer and provider of life science and advanced materials research tools based on x-ray technology. Bruker Daltonics is a leading developer and provider of innovative life science tools based on mass spectrometry. For more information, please visit www.bruker-biosciences.com

ABOUT PANATecs

PANATecs GmbH was founded in 2004 as a spin-off from the University of Tuebingen. The company combines a highly experienced staff of mass spectrometrists, peptide chemists, structural biologists, and immunologists with a modern core facility. PANATecs offers services in biomarker discovery, identification and validation in the field of clinical proteomics and develops novel tools for the specific enrichment and detection of disease-related proteins. In December 2005 PANATecs founded the Center for Clinical Mass Spectrometry, thus uniting clinical expertise with bioanalytical know-how to provide an optimal environment for clinical and protein sample analysis. For more information, please visit www.panatecs.com

ABOUT THE COOPERATIVE CENTER OF RHEUMATOLOGY

The Cooperative Center of Rheumatology, located in the Department of Nephrology and Rheumatology at the Faculty of Medicine of the Georg-August-University Goettingen, is a member of the German Society of Rheumatology. A large number of different departments and clinics as well as ambulatory physicians collaborate in this Center. The Cooperative Center of Rheumatology takes care of more than one million people in the region and has all modern facilities to diagnose and treat patients with rheumatoid arthritis and associated diseases. Furthermore, the Center has different research programs to detect and investigate the early onset of rheumatoid arthritis.

CAUTIONARY STATEMENT OF BRUKER BIOSCIENCES

Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. Any forward-looking statements contained herein are based on current expectations, but are subject to a number of risks and uncertainties. The factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to the Company's reorganization strategies, integration risks, failure of conditions, technological approaches, product development, market acceptance, cost and pricing of the Company's products, changes in governmental regulations, capital spending capital spending

Spending for long-term assets such as factories, equipment, machinery, and buildings that permits the production of more goods and services in future years.
 and government funding policies, FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 and other regulatory approvals to the extent applicable, competition, the intellectual property of others, patent protection and litigation An action brought in court to enforce a particular right. The act or process of bringing a lawsuit in and of itself; a judicial contest; any dispute.

When a person begins a civil lawsuit, the person enters into a process called litigation.
. These and other factors are identified and described in more detail in our filings with the SEC, including, without limitation, our annual report on Form 10-K Form 10-K

A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information.


Form 10-K

See 10-K.
 for the year ended December 31, 2004, our most recent quarterly reports on Form 10-Q Form 10-Q

See 10-Q.
 and our current reports on Form 8-K. We disclaim any intent or obligation to update these forward-looking statements.
COPYRIGHT 2005 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2005, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Dec 20, 2005
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