Bruker Daltonics Introduces Unique AccuScreen(TM) Accurate Mass Ion Chromatograms for micrOTOF(TM) ESI-(Q-q-)TOF Systems.ORLANDO, Fla. -- AccuScreen yields superior MS and MS/MS MS/MS Tandem Mass Spectroscopy MS/MS Multistage Mass Spectrometry data for target compound screening in complex matrices with increased specificity and molecular formula determination At Pittcon 2006, Bruker Daltonics today announces the new and unique AccuScreen(TM) method for high resolution, accurate mass extracted ion chromatograms on its micrOTOF(TM) ESI-TOF and micrOTOF-Q(TM) ESI-Q-q-TOF mass spectrometers. AccuScreen yields superior LC-MS and LC-MS/MS performance in target compound analyses in complex matrices, such as body fluids, complex small molecule libraries, quantitative proteomics, etc. Applications of AccuScreen include ADME/tox studies in drug development, biomarker analysis, quantitative proteomics and other areas such as forensic high-resolution screening for drugs of abuse, poisons or toxic chemicals. Whether the assay is quantitative or qualitative in nature, the AccuScreen accurate mass ion chromatograms (AMICs) dramatically reduce chemical background interference and greatly improve specificity over normal +/- 0.5 Dalton (Da) extracted ion chromatograms. The AccuScreen AMICs can be generated with a tolerance down to +/- 0.002Da, a unique capability enabled by the advanced design of the micrOTOF-series with unprecedented external calibration of better than 5ppm, and high resolution better than 10,000 (FWHM FWHM Full Width at Half Maximum ) over the entire MS/(MS) mass range run and across the full dynamic range of a typical HPLC HPLC high-performance liquid chromatography. HPLC high performance liquid chromatography. HPLC High-performance liquid chromatography Lab instrumentation A highly sensitive analytic method in which analytes are placed run. The bench-top micrOTOF-series features outstanding sensitivity and stability, as well as mass accuracy of better than 3 ppm with internal calibration, and mass resolution greater than 15,000 (FWHM), outperforming traditional floor-standing Q-q-TOF mass spectrometers. Since its introduction one year ago, the micrOTOF-Q has quickly become very successful due to its outstanding performance in a convenient, robust bench-top format, essentially changing the market paradigm for Q-q-TOF mass spectrometers. Dr. Ian Sanders, Vice President of Bruker Daltonics, explained: "In contrast to traditional target-specific triple-quadrupole mass spectrometry mass spectrometry or mass spectroscopy Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields. assays, AccuScreen enables screening approaches without the need to know the target compounds already before the analysis. In particular, new targets can be screened for and can be identified based of the micrOTOF's unique sigmaFit(TM) molecular formula determination even months after the analysis. While in triple-quad MS/MS target screening most of the available molecular information simply cannot be measured and is discarded, for AccuScreen using high-resolution AMICS the number of screening targets is virtually unlimited." Pittcon 2006, the 57th Pittsburgh Conference and Exposition on Analytical Chemistry and Applied Spectroscopy, is being held from March 13-16 in Orlando, Florida in the Orange County Convention Center The Orange County Convention Center (OCCC) is the primary public convention center in Central Florida. The large complex is located on International Drive, a major tourist area in Orlando, Florida. . Bruker Daltonics will exhibit at booth #3155. ABOUT BRUKER BIOSCIENCES (NASDAQ NASDAQ in full National Association of Securities Dealers Automated Quotations U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on : BRKR BRKR Breaker ) Bruker BioSciences Corporation Bruker Biosciences Corporation is a Massachusetts-based company formed in 2003 which develops and manufactures scientific instrumentation for academic research and industrial use. , headquartered in Billerica, Massachusetts, is the publicly traded parent company of Bruker Daltonics Inc. and Bruker AXS Inc. Bruker AXS is a leading developer and provider of life science, materials research, and industrial X-ray analysis tools. Bruker Daltonics is a leading developer and provider of innovative life science tools based on mass spectrometry. Bruker Daltonics also offers a broad line of nuclear, biological and chemical (NBC NBC in full National Broadcasting Co. Major U.S. commercial broadcasting company. It was formed in 1926 by RCA Corp., General Electric Co. (GE), and Westinghouse and was the first U.S. company to operate a broadcast network. ) detection products for defense and homeland security. For more information, please visit www.bruker-biosciences.com CAUTIONARY STATEMENT Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and of 1995. Any forward-looking statements contained herein are based on current expectations, but are subject to a number of risks and uncertainties. The factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to the Company's reorganization strategies, integration risks, failure of conditions, technological approaches, product development, market acceptance, cost and pricing of the Company's products, changes in governmental regulations, capital spending and government funding policies, FDA FDA abbr. Food and Drug Administration FDA, n.pr See Food and Drug Administration. FDA, n.pr the abbreviation for the Food and Drug Administration. and other regulatory approvals to the extent applicable, competition, the intellectual property of others, patent protection and litigation An action brought in court to enforce a particular right. The act or process of bringing a lawsuit in and of itself; a judicial contest; any dispute. When a person begins a civil lawsuit, the person enters into a process called litigation. . These and other factors are identified and described in more detail in our filings with the SEC, including, without limitation, our respective annual reports on Form 10-K, our most recent quarterly reports on Form 10-Q, and our current reports on Form 8-K. We disclaim any intent or obligation to update these forward-looking statements. |
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