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Bruker Daltonics Introduces High Performance Compact Vertical MALDI-TOF/TOF Mass Spectrometer at IMSC.


PRAGUE, Czech Republic -- New Autoflex III Offers Unique Smartbeam Technology, a 4-fold Sensitivity Increase and Enhanced PAN Mass Resolution Over Broad Mass Range of Peptides

At the 17th International Mass Spectrometry mass spectrometry
 or mass spectroscopy

Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields.
 Conference, Bruker Daltonics today announces its new autoflex(R) III smartbeam(TM) vertical MALDI-TOF MALDI-TOF Matrix Assisted Laser Desorption Ionization - Time of Flight  or TOF/TOF mass spectrometer. Mass resolution and accuracy, sensitivity, analytical versatility and reliability have all been further enhanced in the new autoflex III smartbeam instruments for optimum performance in expression proteomics, quantitative proteomics, as well as in peptide/protein biomarker discovery, identification and validation.

Based on Bruker Daltonics' unique and proprietary smartbeam(TM) laser technology, the novel autoflex III series is particularly well suited for MALDI MALDI Matrix-Assisted Laser Desorption/Ionization  molecular imaging applications in in-vitro imaging of peptide and protein biomarker distributions in tissue sections, e.g. in tumor regions. The smartbeam laser allows variable repetition rates from 1 Hz up to 200 Hz, with a computer-controlled, adjustable laser focus size and unrivalled spatial resolution (Data West Research Agency definition: see GIS glossary.) A measure of the accuracy or detail of a graphic display, expressed as dots per inch, pixels per line, lines per millimeter, etc. It is a measure of how fine an image is, usually expressed in dots per inch (dpi). .

In addition to a four-fold sensitivity increase compared to the previous autoflex II, the latest autoflex III offers major advances in mass resolution over a broad mass range, using panoramic PAN(TM) technology, the same technology used in Bruker Daltonics' top-of-the-line ultraflex(TM) TOF/TOF series. Mass spectra with the simultaneous highest resolution over an extended mass range greatly increase success rates in protein database identifications, without the need to optimize instrument parameters. With Bruker Daltonics' well-established LIFT(TM) TOF/TOF ion optics and unique smartbeam(TM) technology for unprecedented analytical versatility in sample types, matrices, etc., the high-performance autoflex III and ultimate-performance ultraflex III are the preferred MALDI systems for quantitative expression proteomics, top-down proteomics, intact protein analysis, LC-MALDI workflows and clinical proteomics.

The new autoflex III is fully integrated into Bruker Daltonics solution packages such as ClinProt(TM) for biomarker discovery, MALDI Molecular Imager(TM) for biomarker distribution in tissue section, its Proteineer(TM) line (the 2D gel-based proteomics suite), and Proteineer LC(TM) line (the LC-based proteomics suite).

Dr. Michael Schubert, Executive Vice President of Bruker Daltonics, commented: "We have now implemented many of the cutting-edge technologies from our top-of-the-line ultraflex MALDI-TOF/TOF, like smartbeam laser, PAN resolution over a broad mass range, and 4x sensitivity enhancements, into our compact vertical autoflex III system to perform at the highest level. Moreover, statistical biomarker data obtained with the autoflex III can now be merged easily with molecular images for in-depth investigation of the spatial distribution of peptides and proteins in tissues."

For further information on IMSC IMSC Integrated Media Systems Center (University of Southern California)
IMSC Information Management Steering Committee
IMSC International Mobile Satellite Conference
IMSC Interworking Mobile Switching Center
, please visit www.imsc2006.org

ABOUT BRUKER BIOSCIENCES (NASDAQ NASDAQ
 in full National Association of Securities Dealers Automated Quotations

U.S. market for over-the-counter securities. Established in 1971 by the National Association of Securities Dealers (NASD), NASDAQ is an automated quotation system that reports on
: BRKR BRKR Breaker )

Bruker BioSciences Corporation Bruker Biosciences Corporation is a Massachusetts-based company formed in 2003 which develops and manufactures scientific instrumentation for academic research and industrial use.  in Billerica, Massachusetts is the parent company of Bruker AXS Inc., Bruker Daltonics Inc. and Bruker Optics, Inc. Bruker AXS is a leading developer and provider of life science, materials research and industrial X-ray analysis tools. Bruker Daltonics is a leading developer and provider of innovative life science tools based on mass spectrometry, and also offers a broad line of nuclear, biological and chemical (NBC NBC
 in full National Broadcasting Co.

Major U.S. commercial broadcasting company. It was formed in 1926 by RCA Corp., General Electric Co. (GE), and Westinghouse and was the first U.S. company to operate a broadcast network.
) detection products for homeland security. Bruker Optics is a leading developer, manufacturer and provider of research, analytical and process analysis instruments and solutions based on infrared and Raman molecular spectroscopy technology. For more information, please visit www.bruker-biosciences.com

CAUTIONARY STATEMENT

Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. Any forward-looking statements contained herein are based on current expectations, but are subject to a number of risks and uncertainties. The factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to the companies' reorganization strategies, integration risks, failure of conditions, technological approaches, product development, market acceptance, cost and pricing of the companies' products, changes in governmental regulations, capital spending capital spending

Spending for long-term assets such as factories, equipment, machinery, and buildings that permits the production of more goods and services in future years.
 and government funding policies, FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 and other regulatory approvals to the extent applicable, competition, the intellectual property of others, patent protection and litigation An action brought in court to enforce a particular right. The act or process of bringing a lawsuit in and of itself; a judicial contest; any dispute.

When a person begins a civil lawsuit, the person enters into a process called litigation.
. These and other factors are identified and described in more detail in our filings with the SEC, including, without limitation, our respective annual reports on Form 10-K, our most recent quarterly reports on Form 10-Q, and our current reports on Form 8-K. We disclaim any intent or obligation to update these forward-looking statements.
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No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Aug 27, 2006
Words:714
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