Breault Research Brings Realistic Skin Modeling into the Realm of Virtual Prototyping; ASAP Optical Software Models Light Propagation, Scattering and Absorption in Human Skin.

TUCSON, Ariz. -- Breault Research Organization (BRO) has developed a robust, multi-layered skin model for use within its Advanced Systems Analysis Program (ASAP(R)).

ASAP Optical Software is a proven research tool for the development of bio-optical devices such as confocal microscopes and fluorescence-imaging systems. These and other bio-optical systems are sometimes made to observe complex optical phenomena in biological tissues. To facilitate understanding and development of emergent bio-optical systems, BRO is implementing realistic tissue phantoms in optical software, beginning with an advanced skin-modeling technique.

The Realistic Skin Model (RSM(TM)) is capable of modeling the major layers of human skin -- stratum corneum, epidermis, dermis, and hypodermis -- independently. This multi-layered approach allows layer-by-layer customization of models, providing a unique tissue model tailored to precise specifications.

Built into the RSM are options for adjusting concentrations of light-absorbing molecules, or chromophores, in each skin layer. This feature opens up a wide array of possibilities for disease and disorder modeling.

According to Paul Holcomb, a BRO biomedical engineer developing the RSM, "The amount of oxy- and deoxy-hemoglobin can be adjusted to examine the effects of oxygen deprivation on skin optical properties, or the amount of bilirubin can be increased to determine the effects of jaundice, a common symptom of liver disease."

"The implementation of realistic tissue modeling within the ASAP virtual-prototyping environment creates many important opportunities for research and development," added Holcomb.

BRO's tissue models can be integrated with pre-existing optical designs for accurate characterization of system functionality and optical phenomena in tissue samples. Simultaneous modeling of optical systems and tissue makes virtual analysis of the light-tissue interface a fast, cost-effective alternative to laboratory studies.

BRO plans to create many tissue models, such as the RSM, to assist researchers in quickly and accurately characterizing optical systems and the biological samples they observe.

About Breault Research Organization (BRO)

BRO is an optical engineering firm of global reach and reputation, providing an international array of clients with innovative solutions. Industries serviced by BRO include: aerospace, automotive, biotechnology, consumer electronics, defense, medical, semiconductor, and telecommunications sectors. BRO's Advanced Systems Analysis Program (ASAP) is the leading program uniting geometrical and physical optics with full 3D models of optical and mechanical systems. More than 20 years of continuous enhancement gives ASAP incomparable simulation capabilities for the physics of optical systems. BRO provides optics training, technical support & documentation, and enterprise consulting services. BRO sets true foundations for today's solutions and the future's advance.