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Breast milk battles thrush in infants.


A mother's milk may be the best medicine for newborn infants with AIDS.

Human breast milk inhibits the growth of yeast spores, the source of a painful fungal infection fungal infection, infection caused by a fungus (see Fungi), some affecting animals, others plants. Fungal Infections of Human and Animals
 of the mouth and throat in infants, according to research presented last week.

Called thrush, the infection affects approximately 5 percent of all newborns. Babies born with compromised immune systems are at much higher risk of developing thrush.

The yeast responsible, Candida albicans Candida albicans,
n a pathogenic yeast, which is the causal agent of thrush, vaginal infections, and systemic candidiasis.

Candida albicans 
, is one of the leading sources of infection in pediatric AIDS pediatric AIDS AIDS acquired HIV perinatally or by 'vertical'–maternal-infant transmission; children with PAIDS may become symptomatic–lymphoid interstitial pneumonia, encephalopathy, recurrent bacterial infection, Candida , says Annalee S. Lucena of Miami University in Oxford, Ohio, who presented the work with her colleague Marcia R. Lee. The sprouting fungus burrows into soft tissue, forming white patches at the back of the throat. Nursing becomes painful and babies often stop feeding. "Once these babies have [thrush], there is very little chance of survival," says Lucena.

Normally a benign inhabitant INHABITANT. One who has his domicil in a place is an inhabitant of that place; one who has an actual fixed residence in a place.
     2. A mere intention to remove to a place will not make a man an inhabitant of such place, although as a sign of such intention he
 of the body, the fungus is also responsible for vaginal yeast infections in adult women and diaper rash Diaper Rash Definition

Dermatitis of the buttocks, genitals, lower abdomen, or thigh folds of an infant or toddler is commonly referred to as diaper rash.
 in infants. Babies commonly pick up the fungus in the birth canal birth canal
n.
The passage through which the fetus is expelled during parturition, leading from the uterus through the cervix, vagina, and vulva. Also called parturient canal.
. The yeast can reside harmlessly in moist folds of their skin. A healthy immune system usually keeps C. albicans in check.

Lucena added a yeast solution to diluted and full-strength breast milk. Without milk, yeast germinates within 2 days. Although the yeast stayed alive in the full-strength and diluted milk, even low dilutions of milk--down to 1 part in 750--inhibited yeast germination germination, in a seed, process by which the plant embryo within the seed resumes growth after a period of dormancy and the seedling emerges. The length of dormancy varies; the seed of some plants (e.g.  and growth.

Human breast milk contains antibodies that are absorbed by the baby's disgestive tract and help the young immune system recognize invaders. When Lucena removed the most abundant antibody, the milk's antifungal properties disappeared. Other tests indicated, however, that this antibody alone can't defeat the yeast.

Some antifungal medications can control thrush, but they're harmful and are only used as last resort, even in adults. With these powerful drugs, says Lucena, "the cliche is that you either kill the fungus or you kill the person." She contends that breast milk from a woman who does not have AIDS would be a good alternative or addition to the arsenal of antifungal drugs for thrush in infants.
COPYRIGHT 2001 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2001, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Science News
Article Type:Brief Article
Date:Jun 2, 2001
Words:353
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