Breast Cancer Is The Leading Cause Of Cancer-Related Mortality Among Women Worldwide.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c54057) has announced the addition of "Breast Cancer Drug Pipeline Update 2008" to their offering. High unmet needs still persist for this tumor type. Despite recent drug approvals in the adjuvant and metastatic setting, the overall survival remains below five years. There are today more than 340 therapeutics targeting breast cancer, from early preclinical to marketed drugs. Breast Cancer Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 165 different targets. These targets are further categorized on the CD-ROM CD-ROM: see compact disc. CD-ROM in full compact disc read-only memory Type of computer storage medium that is read optically (e.g., by a laser). by 49 classifications of molecular function and with pathway referrals to BioCarta, KEGG and NetPath. Read more below on how the Breast Cancer Drug Pipeline Update is organized. How May Drug Pipeline Update Be of Use? Show investors/board/management that you are right on top of drug development progress in your therapeutic area. Find competitors, collaborations partners, M&A candidates etc. Jump start competitive drug intelligence operations Excellent starting point for world wide benchmarking Compare portfolio and therapy focus with your peers Speed up pro-active in-/out licensing strategy work Fast and easy way of tracking drugs using search engines; just one click from inside the application and you may search the World Wide Web and PubMed for any drug. Drug Pipeline Update is delivered to you as a CD-ROM application, which requires no installation on your computer. Please read more about application features and system requirements below. Drug Pipeline Update at a Glance Investigators Includes more than 245 principal investigators plus their collaborators. There is direct access from inside the application to web pages of all principal investigators. Note: You are able to sort and find drugs according to investigators and partners from drop-down menus in the application. You may also sort and find drugs according to country of investigator. Drug name & Synonyms Lists commercial, generic and code names for drugs. In all more than 500 names Developmental stage This Drug Pipeline Update contains more than 340 drugs in active development for the treatment of breast cancer: 50 marketed drugs * 10 projects in Phase III * 110 projects in Phase II * 65 projects in Phase I * 85 projects in Preclinical Note: You are able to sort and find drugs according to developmental stage from drop-down menu in the application. Indications Included breast cancer drugs are also in development for over 120 other listed indications Note: You are able to sort and find drugs according to type of indication from drop-down menu in the application. Targets Identified drugs are linked to more than 165 different targets, divided into 49 classifications of molecular function: * Catalytic activity * Cell adhesion molecule Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion. activity * Chaperone chaperone /chap·er·one/ (shap´er-on) someone or something that accompanies and oversees another. molecular chaperone activity * Chemokine activity * Complement activity * Cysteine-type peptidase peptidase /pep·ti·dase/ (pep´ti-das) any of a subclass of proteolytic enzymes that catalyze the hydrolysis of peptide linkages; it comprises the exopeptidases and endopeptidases. pep·ti·dase n. activity * Cytokine activity * DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. binding * DNA repair protein * DNA topoisomerase activity * DNA-directed DNA polymerase activity * Extracellular matrix structural constituent * G-protein coupled receptor activity * Glutathione transferase transferase /trans·fer·ase/ (trans´fer-as) a class of enzymes that transfer a chemical group from one compound to another. trans·fer·ase n. activity * Growth factor activity * Hormone activity * Isomerase isomerase /isom·er·ase/ (i-som´er-as) a major class of enzymes comprising those that catalyze the process of isomerization. i·som·er·ase n. activity * Kinase activity * Kinase binding * Kinase regulator activity * Ligand-dependent nuclear receptor activity * Ligase ligase /li·gase/ (li´gas) (lig´as) any of a class of enzymes that catalyze the joining together of two molecules coupled with the breakdown of a pyrophosphate bond in ATP or a similar triphosphate. activity * Lipid kinase activity * Lipid phosphatase activity * Metallopeptidase activity * Molecular function unknown * Motor activity * Oxidoreductase oxidoreductase /ox·i·do·re·duc·tase/ (ok?si-do-re-duk´tas) any of a class of enzymes that catalyze the reversible transfer of electrons from a substrate that becomes oxidized to one that becomes reduced (oxidation-reduction, or redox activity * Phosphoric phos·phor·ic adj. Of, relating to, or containing phosphorus, especially with a valence of 5 or a valence higher than that of a comparable phosphorous compound. diester hydrolase hydrolase /hy·dro·lase/ (hi´dro-las) one of the six main classes of enzymes, comprising those that catalyze the hydrolytic cleavage of a compound. hy·dro·lase n. activity * Protein binding * Protein serine/threonine kinase activity * Protein threonine/tyrosine kinase activity * Protein-tyrosine kinase activity * Receptor activity * Receptor binding * Receptor signaling complex scaffold activity * Receptor signaling protein serine/threonine kinase activity * Serine-type peptidase activity * Structural constituent of cytoskeleton cytoskeleton System of microscopic filaments or fibres, present in the cytoplasm of eukaryotic cells (see eukaryote), that organizes other cell components, maintains cell shape, and is responsible for cell locomotion and for movement of the organelles within it. * Structural molecule activity * Superoxide dismutase activity * T cell receptor The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is generally responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. activity * Transcription factor activity * Transcription regulator activity * Transferase activity * Translation regulator activity * Transmembrane receptor activity * Transmembrane receptor protein tyrosine kinase activity * Transporter activity For more information, visit http://www.researchandmarkets.com/reports/c54057 |
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