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Breakthrough in war on cancer; UNIVERSITY: Scientists hope to diagnose killer liver condition quicker.


Byline: By Alison Dayani

SCIENTISTS at Birmingham University Birmingham University, at Birmingham, England; founded 1900. It has faculties of arts, science, engineering, medicine and dentistry, commerce and social science, law, and education and continuing studies.  are close to "breaking the code" for a liver cancer Liver Cancer Definition

Liver cancer is a relatively rare form of cancer but has a high mortality rate. Liver cancers can be classified into two types.
 test.

Researchers at the Edgbastonbased faculty are developing the blood test that will help diagnose liver cancer much quicker and save lives.

Laboratory work so far shows the test has the potential to reveal liver cancer in high risk patients before symptoms even show up.

Prof Philip Johnson, a lead researcher based in the university's Cancer Research UK Institute for Cancer Studies, said: "We've shown that the right combination of technology and computer analysis can 'break the code' of liver cancer and distinguish people with early liver cancer from those without the disease.

"Our method was more accurate than the existing liver cancer blood test.

"However, this is only the first step on a long road towards a test that can be reliably used for the many people at risk of developing primary liver cancer.

"We want to improve the technology to make the test even more accurate. The work to date shows that our test has the potential to reveal liver cancer before symptoms show up."

Liver cancer is the sixth most common cancer in the world and has claimed the lives of millions including Cilla Black's husband Bobby in 1999.

There is more hope for sufferers the earlier cancer is spotted and treated.

High risk groups, such as people with cirrhosis of the liver Cirrhosis of the liver
A type of liver disease, most often caused by chronic alcohol abuse. It is characterized by scarring of the liver, which leads to an increase in the blood pressure in the portal veins.

Mentioned in: Bleeding Varices
, can be monitored currently, but tests are not sensitive enough to detect the disease early. Liver diseases, including cirrhosis of the liver and hepatitis from the hepatitis B Hepatitis B Definition

Hepatitis B is a potentially serious form of liver inflammation due to infection by the hepatitis B virus (HBV). It occurs in both rapidly developing (acute) and long-lasting (chronic) forms, and is one of the most common chronic
 and C viruses, are currently monitored through ultrasound scans and a test for the presence of a single protein called alpha-fetoprotein.

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PIONEERING... scientists at Birmingham University are close to 'breaking the code' for a liver cancer test.
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Publication:Birmingham Mail (England)
Date:Jan 26, 2006
Words:301
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