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Boston Probes Announces The Issuance Of US Patent 6,110,676 For New Use Of PNA Probe Technology.


Business Editors & Health/Medical Writers

BEDFORD, Mass.--(BW HealthWire)--Sept. 25, 2000

Boston Probes Inc. today announces the issuance of US PAT NO. 6,110,676 jointly to Boston Probes & DAKO A/S. This patent describes a new and powerful application of Peptide Nucleic Acid nucleic acid, any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.  (PNA PNA Palestinian National Authority
PNA Phoneline Networking Alliance
PNA Peptide Nucleic Acid
PNA Personal Navigation Assistant
PNA Pacific/North American
PNA Polish National Alliance (established 1880 in Chicago, Illinois) 
) probe technology.

The broadly claimed methods result in a substantial reduction in the non-specific signal in the assay as compared with conventional nucleic acid probe based hybridization hybridization /hy·brid·iza·tion/ (hi?brid-i-za´shun)
1. crossbreeding; the act or process of producing hybrids.

2. molecular hybridization

3.
 assays to thereby improve the performance of the probe based assays far beyond that obtainable by mere optimization of stringency conditions. Such PNA probe based methods are particularly useful for any type of single nucleotide polymorphism Noun 1. single nucleotide polymorphism - (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily successful enough to recur in a  (SNP SNP Scottish National Party

Noun 1. SNP - (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily
) analysis. Thus, the patented methods can be applied to the development and commercialization of products in several areas including: basic research, genomics, forensic analysis, pharmaceutical discovery as well as food and environmental testing.

" The issuance of this patent is a major milestone in the history of our company," says Jack T. Johansen, Ph.D., President and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Boston Probes. "We believe our innovative PNA technology, supported by key patents like this one, will accelerate the development of applications for PNA probes and foster the acceptance of PNA as a superior probe technology."

Boston Probes is a development stage company located in Bedford, Massachusetts Bedford is a town in Middlesex County, Massachusetts, United States. It is within the Greater Boston area, some 15 miles north-west of the city of Boston. The population of Bedford was 12,595 at the 2000 census. . Boston Probes has, since 1996, been developing PNA probe technologies for use in agriculture, human and veterinary diagnostics as well as the detection of microorganisms in foods, beverages, water, the environment and other industrial processes such as pharmaceutical manufacturing.

In addition to the sale of its own products, Boston Probes is forming strategic partnerships that will allow its partners to quickly exploit the advantages of PNA technology within their products and thereby achieve a substantial competitive advantage in their respective strategic markets. The company commands an extensive PNA related intellectual property portfolio as derived from its own innovations as well as the in-licensing of PNA related inventions from DAKO A/S, PNA Diagnostics A/S and the Applied Biosystems Group of PE Corporation.
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Publication:Business Wire
Geographic Code:1USA
Date:Sep 25, 2000
Words:337
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