Bone Disease: Report on the Web.A 54-page background report on bone disease in persons with HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States. (including avascular necrosis Avascular necrosis is a disease resulting from the temporary or permanent loss of the blood supply to the bones. Without blood, the bone tissue dies and causes the bone to collapse. If the process involves the bones near a joint, it often leads to collapse of the joint surface. , and also osteopenia) can be found in Bone Metabolism and HIV Disease Meeting Report, published by the Forum for Collaborative HIV Research. Contents include: * Bone disease and HIV * Overview of the local regulation of bone * Crosstalk: Bone and the Immune System immune system Cells, cell products, organs, and structures of the body involved in the detection and destruction of foreign invaders, such as bacteria, viruses, and cancer cells. Immunity is based on the system's ability to launch a defense against such invaders. * Cytokine Cytokine Any of a group of soluble proteins that are released by a cell to send messages which are delivered to the same cell (autocrine), an adjacent cell (paracrine), or a distant cell (endocrine). aspects of bone biology * Increased prevalence of avascular necrosis in HIV-infected adults, and * Bone metabolism in HIV Disease: New and old paradigms This paper reports on a meeting that occurred August 29, 2000, so readers should also check more recent information. The report is available at http://www.hivforum.org; currently it's under "Publications and Reports," then under "Metabolic Abnormalities." Note that Forum reports are more focused on research policy than on practical treatment or management information. |
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