Blood points to pollution's heart risks.Hospitals admit more patients for heart problems on days when air pollution is bad. A new study reveals that as airborne concentrations of fine dust particles climb, so do three blood factors that increase an individual's heart attack risk. Joel Schwartz of the Harvard School of Public Health The Harvard School of Public Health is (colloquially, HSPH) is one of the professional graduate schools of Harvard University. Located in Longwood Area of the Boston, Massachusetts neighborhood of Mission Hill, next to Harvard Medical School and Cambridge, Massachusetts, in Boston correlated blood data for more than 5,000 men and women with measurements of air pollution on the day their blood had been drawn. The randomly selected adults were among participants in a large federal survey on diet and health. To assess pollution exposures, Schwartz collected readings from all air-monitoring stations in and around each volunteer's home county, giving more weight to the nearer stations. He then correlated data for the pollutants pollutants see environmental pollution. with measurements of three agents in the volunteers' blood that can signal heart problems: platelets and fibrinogen Fibrinogen The major clot-forming substrate in the blood plasma of vertebrates. Though fibrinogen represents a small fraction of plasma proteins (normal human plasma has a fibrinogen content of 2–4 mg/ml of a total of 70 mg protein/ml), its conversion , both of which promote blood clotting blood clotting, process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings. , and white blood cells White blood cells A group of several cell types that occur in the bloodstream and are essential for a properly functioning immune system. Mentioned in: Abscess Incision & Drainage, Bone Marrow Transplantation, Complement Deficiencies , which can signal that plaque inside arteries may soon rupture rupture, in medicine: see hernia. and block vessels. In a June supplement to ENVIRONMENTAL HEALTH PERSPECTIVES, Schwartz reports that of all the pollutants measured, only fine particulates--those smaller than 10 micrometers in diameter--were associated with higher than normal concentrations of these blood agents. The size of the rise increased with dose. Accounting for people's diet, smoking, exposure to indoor pollution, and income didn't diminish the "robust" link, says Schwartz. These data "imply that important cardiovascular factors can be modified by airborne particles at commonly occurring concentrations," Schwartz concludes. |
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