Biting The Dust -- Is Lipicard's Niastin(R) Next After Pfizer's Torcetrapib?HYDERABAD, India -- With dramatic discontinuation of Torcetrapib development by Pfizer, questions are raised about other new therapies targeting HDL HDL - High Density Lipoprotein (so-called 'good' cholesterol) HDL - Hab Dich Lieb HDL - Handle HDL - Hardware Description Language HDL - Hardware Design Language HDL - Harry Diamond Laboratories (US Army Research Laboratory) HDL - Hierarchical Design Language HDL - Holding Design Load HDL - Hospital Distrital de Lamego (Portugal) HDL - Huey, Dewey and Louie HDL - Hypothesis Driven Lexical Adaptation increase including Lipicard's Niastin - combination of novel NCE's for integrated Cholesterol Management. Niastin[R] is the latest drug being developed for Integrated Cholesterol Management through Lipicard's novel platform technology for producing high therapeutic index drugs - drugs that are safer and more efficacious. Prasad Sambaru CEO of Lipicard talking on the dramatic events of Torcetrapib said that it is very unfortunate that Pfizer has to end the development of Torcetrapib after incurring such huge costs. He lauded the way Pfizer has handled the Torcetrapib situation. He also added that developments at Pfizer will not have any effect on Niastin developments as the mechanism of action of Niastin and Torcetrapib are totally different, in fact, Niastin program has been put on fast track after the withdrawal of Torcetrapib by Pfizer. The lipid management and control is effected through a two pronged attack - first reducing LDL LDL - Low Density Lipoprotein (so-called 'bad' cholesterol) LDL - Lightwave Data Links (AT&T) LDL - Linux Distribution List LDL - Litho Density Log (Oil Industry) LDL - Loudness Discomfort Level (audiology) LDL - Low Density Level (asset supply management) LDL - Low Density Protein LDL - Lower Detection Limit LDL - Lower Deviation Level and total cholesterol using Statins, and the other is to increase the HDL Cholesterol using Niacin niacin /ni·a·cin/ (ni´ah-sin) nicotinic acid; a water-soluble vitamin of the B complex required by the body for the formation of the coenzymes NAD and NADP, important in biochemical oxidations; used to prevent and treat pellagra and to treat hyperlipidemia. etc. Both Statins and Niacin also increase the HDL and reduce the LDL, VLDL VLDL - Very Low Density Lipoprotein respectively, but predominantly Statins decrease LDL and Niacin increases HDL. Niastin[R] is combination of novel NCE's for increasing the HDL as well as reducing the LDL and VLDL lipoproteins. When compared to Niacin and Statin combination drugs in the market, Niastin is expected to be more efficacious with less toxic side effects including muscle and liver toxicity and flushing. Niastin[R] is being produced using the same novel platform technology that produced the other high therapeutic drugs - Platrol[R] (Safe Antiplatelet an·ti·plate·let (  n t -pl t drug), KeraKlear[R] (Safe and clear solution for Keratoconjuctivities), etc. About Lipicard Technologies: Lipicard Technologies Limited develops innovative and novel High Therapeutic Index Drugs for Lipid management and cardio protection in collaboration with Life Enhancing Technologies LLC. USA. PLATROL[R] is the first safe antiplatelet drug being developed for cardio-protection. Next in line are the integrated Lipid management drug Niastin for increasing HDL and lowering LDL, and safe NSAIDs. PLATROL[R] is registered trademarks of Life Enhancing Technologies. |
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