Biosite, Inc., ANSYS, Inc. Added To S&P SmallCap 600 Index.

Business Editors

NEW YORK--(BUSINESS WIRE)--Feb. 20, 2002

Biosite, Inc. (NASD:BSTE) and ANSYS, Inc. (NASD:ANSS) will replace Organogenesis, Inc. (AMEX:ORG) and Mutual Risk Management (NYSE:MM) in the S&P SmallCap 600 Index after the close of trading on Thursday, February 21, 2002. Organogenesis and Mutual Risk Management are being removed for lack of representation.

Biosite, Inc. develops, manufactures and markets diagnostic products that improve the quality of patient care and simplify the practice of laboratory medicine. The company, headquartered in San Diego, California, will be added to the S&P SmallCap 600 GICS (Global Industry Classification Standard) Health Care Equipment sub-industry group.

ANSYS, Inc. develops, markets and supports software solutions for design analysis and optimization in order to accelerate product time to market, improve engineering processes and optimize product quality and safety. The company, headquartered in Canonsburg, Pennsylvania, will be added to the S&P SmallCap 600 GICS Application Software sub-industry group.

      Following is a summary of the announced changes:

              S&P SMALLCAP 600 INDEX - February 21, 2002

           COMPANY      GICS ECONOMIC SECTOR   GICS SUB-INDUSTRY GROUP

 ADDED   Biosite, Inc.       Health Care        Health Care Equipment

         ANSYS, Inc.    Information Technology   Application Software

DELETED Organogenesis, Inc.   Health Care           Biotechnology

         Mutual Risk
         Management            Financials        Multi-line Insurance

Company additions to and deletions from an S&P equity index do not in any way reflect an opinion on the investment merits of the company.

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