Biopharmaceutical Contract Manufacturing: HighTech Business Decisions Report Indicates Improved Quality, Increased Capacity and Emerging Technologies Continue to Fuel Industry Growth.SAN JOSE San Jose, city, United States San Jose (sănəzā`, săn hōzā`), city (1990 pop. 782,248), seat of Santa Clara co., W central Calif.; founded 1777, inc. 1850. , Calif. -- The demand for biopharmaceutical contract manufacturing services continues to expand as pharmaceutical and biotechnology companies Top 100 Biotechnology Companies The following is a list of the top 100 biotechnology companies ranked by revenue. The first nine companies qualify for the list of the top 50 pharmaceutical companies. increasingly rely on contractors to provide more production capacity and a wider range of services. There will be significant changes in the worldwide biopharmaceutical contract manufacturing industry over the next years as contract manufacturers add new capacity and expand their service offerings. In addition new technologies are being deployed that will positively impact yields and productivity, including use of disposables, new host cell systems and perfusion perfusion /per·fu·sion/ (-zhun) 1. the act of pouring over or through, especially the passage of a fluid through the vessels of a specific organ. 2. a liquid poured over or through an organ or tissue. technologies. As the biologics pipeline continues to grow, the biotechnology companies are increasing their use of novel product types such as antibody fragments, conjugates, and fusion proteins  It has been suggested that Recombinant fusion proteins, Oncogene fusion proteins, Chimera (protein) . The seventh industry study published by HighTech Business Decisions, "Biopharmaceutical Contract Manufacturing 2007: Quality, Capacities and Emerging Technologies," reports in 2007 and 2008, that contractor capacity utilization Capacity Utilization measures the rate at which a firm makes use of their capital productive capacities, such as factories and machinery. Capacity Utilization generally rises when the economy is healthy and falls when demand softens. will increase over the next two years; however, longer term, supplies will be readily available as new capacity continues to come on-line and process improvements impact productivity. William Downey, President of HighTech Business Decisions, explains, "We extensively interviewed 41 directors of biomanufacturing at pharmaceutical and biotechnology companies worldwide, and 27 biopharmaceutical contract manufacturers. The biopharmaceutical CMOs are expanding and changing their business models with some of their clients to solve technology and capacity issues going forward. In addition, several CMOs are working to increase manufacturing efficiencies by working with their customers in the areas of cell line development and process development. Others are implementing electronic batch record systems and other systems to boost efficiencies." The market for biopharmaceutical contract manufacturing reached US$2.1B in 2006, and is forecasted to continue on its growth trajectory Trajectory The curve described by a body moving through space, as of a meteor through the atmosphere, a planet around the Sun, a projectile fired from a gun, or a rocket in flight. through 2008. Based on revenues, the top biopharmaceutical CMOs include Avecia Biotechnology, Boehringer Ingelheim GmbH, Diosynth Biotechnology, Lonza Custom Manufacturing and Sandoz GmbH. The report provides in-depth analysis of the dynamic factors impacting the industry, including new equipment and disposable technologies, improved expression levels, increasing competitiveness, changing outsourcing strategies, capacity estimates and forecasts, changes in outsourcing spending and margins, transgenics trans·gen·ics n. (used with a sing. or pl. verb) The study of or methodology used to create transgenic animals or plants. , and biomanufacturing in low-cost regions. The report is 800 pages in length. About HighTech Business Decisions: HighTech Business Decisions is a consulting firm Noun 1. consulting firm - a firm of experts providing professional advice to an organization for a fee consulting company business firm, firm, house - the members of a business organization that owns or operates one or more establishments; "he worked for a specializing in benchmarking studies, customize market analysis and customer loyalty surveys for companies serving pharmaceutical and biotechnology markets. Visit us at www.hightechdecisions.com |
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