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Biophan Releases Positive Animal Study on MYO-VAD(TM).


Data Indicates Promise for Treatment of Heart Failure

ROCHESTER, N.Y. -- Biophan Technologies, Inc. (OTCBB OTCBB

See OTC Bulletin Board (OTCBB).
: BIPH BIPH Bogomoletz Institute of Physiology (National Academy of Sciences; Ukraine) ; FWB (Fixed Wireless Broadband) See fixed wireless. : BTN BTN

In currencies, this is the abbreviation for the Bhutan Ngultrum.

Notes:
The currency market, also known as the Foreign Exchange market, is the largest financial market in the world, with a daily average volume of over US $1 trillion.
), a developer of next-generation biomedical technology, in conjunction with MYOTECH, LLC (Logical Link Control) See "LANs" under data link protocol.

LLC - Logical Link Control
, recently presented results of animal studies that indicate the potential of the MYO-VAD cardiac support system to significantly improve the treatment of heart failure. This devastating disease currently has no cure and affects an estimated 5,000,000 Americans each year.

Heart failure is a progressive condition that involves the heart re-shaping, or "remodeling remodeling /re·mod·el·ing/ (re-mod´el-ing) reorganization or renovation of an old structure.

bone remodeling
", into a less effective blood pump. This occurs after the heart has been damaged by any disease or condition that puts extra stress on the heart's muscle or deprives it of blood. High blood pressure, coronary artery disease coronary artery disease, condition that results when the coronary arteries are narrowed or occluded, most commonly by atherosclerotic deposits of fibrous and fatty tissue.  and heart attacks are typical causes. For example, within 6 years of a recognized heart attack 22% of men and 46% of women will be disabled with heart failure, according to the American Heart Association American Heart Association (AHA),
n.pr a national voluntary health agency that has the goal of increasing public and medical awareness of cardiovascular diseases and stroke, and thereby reducing the number of associated deaths and disabilities.
.

The animal study presented at the recent Cleveland Clinic symposium on heart failure suggests that the MYO-VAD can significantly improve the ability of failing hearts to pump blood, while simultaneously reducing the stress on the heart that accounts for the vicious, progressive cycle of heart failure.

Researchers found that key biomarkers of heart failure increased in animal hearts with induced heart damage, but decreased in animals whose damaged hearts were supported with the MYO-VAD. Investigators concluded that the device "can significantly augment the failing heart while reducing myocardial myocardial /myo·car·di·al/ (-kahr´de-al) pertaining to the muscular tissue of the heart.

myocardial

pertaining to the muscular tissue of the heart (the myocardium).
 stress," and that the device "can provide adequate hemodynamic he·mo·dy·nam·ics  
n. (used with a sing. verb)
The study of the forces involved in the circulation of blood.



he
 support while favorably altering the maladaptive Maladaptive
Unsuitable or counterproductive; for example, maladaptive behavior is behavior that is inappropriate to a given situation.

Mentioned in: Cognitive-Behavioral Therapy
 pathophysiology pathophysiology /patho·phys·i·ol·o·gy/ (-fiz?e-ol´ah-je) the physiology of disordered function.

path·o·phys·i·ol·o·gy
n.
1.
 of heart failure."

According to the American Heart Association, 550,000 new cases of heart failure are diagnosed annually in the U.S. and an estimated 15 million new cases are reported yearly worldwide. Direct and indirect costs of heart failure in the U.S. in 2006 have been estimated at $29 billion.

"Heart failure is most commonly treated with pharmaceuticals, but this approach is ineffective and heart failure remains the number one killer and the most costly condition for the U.S. health care system," said Jeffrey Helfer, President of Biophan's Cardiovascular Division.

According to Mr. Helfer, "The MYO-VAD technology has already demonstrated its ability to support suddenly failing hearts (such as in a heart attack). By favorably altering the progression of heart failure that follows, we believe these results indicate potential for the MYO-VAD to treat a much wider range of patient conditions."

The scientific presentation can be found on the company website at www.biophan.com/myovad_results1206

About the MYO-VAD

The MYO-VAD can be implanted on an arrested or weak heart in approximately three minutes, restoring cardiac output. It consists of a flexible polymer cup that fits around the heart, compressing and expanding both ventricles Ventricles
The two chambers of the heart that are involved in pumping blood. The right ventricle pumps blood into the lungs to receive oxygen. The left ventricle pumps blood into the circulation of the body to deliver oxygen to all of the body's organs and tissues.
. Because it does not come into contact with circulating blood, the MYO-VAD promises to eliminate the serious and potentially fatal complications of clotting and stroke, bleeding, and infection that plague all other Ventricular Assist Devices (VADs).

Due to its technically simple installation and removal requirements, anticipated lower rates of patient complications, and lower device cost, the MYO-VAD is expected to provide a significant reduction in the cost of treating heart failure patients. This promises to extend the physician's ability to treat heart failure and help save thousands of lives.

About Biophan

Biophan is dedicated to providing technologies that offer innovative and competitive advantages to the medical device industry. The Company licenses its technologies which improve the MRI 1. (application) MRI - Magnetic Resonance Imaging.
2. MRI - Measurement Requirements and Interface.
 safety and image compatibility of medical devices to leading device manufacturers. In addition, the Company is commercializing the MYOTECH MYO-VAD(TM), a new, cardiac support system which has significant potential to improve the treatment of many forms of heart disease. Biophan is traded on the OTC market under the symbol BIPH, and is also listed on the Frankfurt Stock Exchange Frankfurt Stock Exchange

The largest of Germany's eight securities exchanges, operated by Deutsche Borse AS.
 under the symbol BTN. For more information on Biophan, please visit our website at www.biophan.com.

Cautionary Statement Regarding Forward-Looking Statements

Certain statements included in this press release may constitute forward-looking statements within the meaning of applicable securities laws. These statements reflect what Biophan anticipates, expects, or believes may happen in the future. Biophan's actual results could differ materially from the outcome or circumstance expressed or implied by such forward-looking statements as a result of a variety of factors including, but not limited to: Biophan's ability to develop its technologies; the approval of Biophan's patent applications; the successful implementation of Biophan's research and development programs; the ability of Biophan to demonstrate the effectiveness of its technology; the acceptance by the market of Biophan's technology and products incorporating such technology; the ability of Biophan to effectively negotiate and enter into contracts with medical device manufacturers for the licensing of Biophan's technology; competition; the ability of Biophan to raise capital to fund its operating and research and development activities until it generates revenues sufficient to do so; and the timing of projects and trends in future operating performance, as well as other factors expressed from time to time in Biophan's periodic filings with the Securities and Exchange Commission (the "SEC"). As a result, this press release should be read in conjunction with Biophan's periodic filings with the SEC, which are incorporated herein by reference. The forward-looking statements contained herein are made only as of the date of this press release, and Biophan undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances.
COPYRIGHT 2006 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2006, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Dec 14, 2006
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