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Biophan Files Twelve New Patents in MRI Safety Expanding Intellectual Property Portfolio to More Than 200 Including International Filings.


ROCHESTER, N.Y -- Innovations Enable Manufacturers of Pacemakers Pacemakers Definition

A pacemaker is a surgically-implanted electronic device that regulates a slow or erratic heartbeat.
Purpose

Pacemakers are implanted to regulate irregular contractions of the heart (arrhythmia).
, Neurostimulators, and Other Medical Devices to Make Products MRI 1. (application) MRI - Magnetic Resonance Imaging.
2. MRI - Measurement Requirements and Interface.
 Safe

Biophan Technologies, Inc. (OTCBB OTCBB

See OTC Bulletin Board (OTCBB).
: BIPH BIPH Bogomoletz Institute of Physiology (National Academy of Sciences; Ukraine) )(Frankfurt/FSE: BTN BTN

In currencies, this is the abbreviation for the Bhutan Ngultrum.

Notes:
The currency market, also known as the Foreign Exchange market, is the largest financial market in the world, with a daily average volume of over US $1 trillion.
) a developer of next-generation biomedical technology Biomedical technology involves the application of engineering and technology principles to the domain of living or biological systems. Usually biomedical denotes a greater stress on problems related to human health and diseases. , has announced the filing of twelve new patents, expanding the Company's extensive intellectual property portfolio to more than 200 patents, applications, or licenses. That total includes 156 pending and issued U.S. patents and another 46 international applications.

The twelve new patents teach how a tiny circuit can be added to minimize dangerous heating which can occur when devices such as pacemaker and neurostimulators leads are exposed to MRI signals. The circuits are powered by the energy in the MRI field and dissipate the energy so that heating does not occur. The circuits can be tuned to specific frequencies, such as the frequencies associated with 1.5 and 3.0 Tesla MRI machines. These circuits have been tested under worst-case conditions on representative devices, and can reduce heating to acceptable levels.

The twelve patents teach a variety of ways that these circuits can reduce heating on many types of medical devices that suffer from MRI safety limitations. These include many implantable devices, such as pacemakers, defibrillators, and neurostimulators, devices used for Parkinson's, epilepsy and pain control, as well as stimulation devices for obesity control, gastrointestinal and bladder control. In addition to implantable devices, this technology applies to devices used in interventional medicine, including catheters, guidewires, and other surgical tools.

"We anticipate a shift over the next several years, where virtually all biomedical bi·o·med·i·cal
adj.
1. Of or relating to biomedicine.

2. Of, relating to, or involving biological, medical, and physical sciences.
 devices currently contraindicated for MRI or experiencing imaging limitations, will be made both safe and compatible for use with MRI. Over $12 billion worth of devices are sold every year with these shortcomings A shortcoming is a character flaw.

Shortcomings may also be:
  • Shortcomings (SATC episode), an episode of the television series Sex and the City
," stated Michael Weiner Michael Weiner can refer to:
  • Michael Savage, the talk-radio host and commentator whose real name is Michael Weiner,
  • Michael Weiner, the academic and professor,
  • Michael Weiner, the actor and composer.
, Biophan CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. . "It is unfortunate when a patient who needs to be staged for a cancer operation is denied access to an MRI machine because they have a pacemaker or other contraindicated implant. An even more tragic situation occurs when a patient is placed in an MRI machine in spite of the contraindication contraindication /con·tra·in·di·ca·tion/ (-in?di-ka´shun) any condition which renders a particular line of treatment improper or undesirable.

con·tra·in·di·ca·tion
n.
 by a physician who is not aware of the implant, or who does not realize that MRI is dangerous when used with these devices. The FDA FDA
abbr.
Food and Drug Administration


FDA,
n.pr See Food and Drug Administration.

FDA,
n.pr the abbreviation for the Food and Drug Administration.
 issued a new warning recently advising radiologists not to place patients with neurostimulators in MRI machines, as one patient went into a coma after the contraindication was not heeded.

"The optimal solution is for manufacturers to make their devices safe for use with MRI. Biophan has the technology to enable this, and there is now significant activity underway to help make future neurostimulators safe for use with MRI, and some increased activity on the part of pacemaker manufacturers," Mr. Weiner said. "There is no ethical justification to continue to ship medical devices that are not safe for use with MRI, and we are pleased to note the increasing activity on the part of many of the major manufacturers to move in this direction."

As previously announced, Biophan has provided a license for MRI safety and image compatibility, covering multiple products to leading medical device manufacturer Boston Scientific The Boston Scientific Corporation (NYSE: BSX) (abbreviated BSC), is a worldwide developer, manufacturer and marketer of medical devices whose products are used in a range of interventional medical specialties, including interventional cardiology, peripheral interventions,  (NYSE NYSE

See: New York Stock Exchange
: BSX BSX Bermuda Stock Exchange
BSX Bandai Satellaview-X
BSX Bicycle Super-X (Cross) 
). Discussions are underway with many other medical device manufacturers in these areas as well.

To learn more about MRI safety and medical devices, visit Biophan's web site at http://www.biophan.com/mrisafety.php or www.biophan.com.

About Biophan Technologies

Biophan develops and markets cutting-edge technologies designed to make biomedical devices safe and image compatible with the magnetic resonance imaging magnetic resonance imaging (MRI), noninvasive diagnostic technique that uses nuclear magnetic resonance to produce cross-sectional images of organs and other internal body structures.  (MRI) environment. The Company develops technologies that enable implanted medical systems such as pacemakers, interventional surgical devices such as catheters and guidewires, and devices such as stents to be safely and effectively imaged under MRI. Biophan is developing these same technologies to provide new MRI contrast agents. Other applications include drug delivery and power systems derived from body heat. Four Biophan technologies include advances in nanotechnology and thin film coatings. Committed to growth through innovation and developmental leadership, Biophan and its licensors now hold a total of 156 U.S. patents, licenses, or applications. This total includes 41 issued U.S. patents, 9 recently-allowed applications that will issue as patents in the near future, and 106 pending applications at various stages of examination at the U.S. Patent and Trademark Office, plus international applications. The patents cover areas including nanotechnology (nanomagnetic particle coatings), medical device designs, radio frequency filters, polymer composites, thermoelectric ther·mo·e·lec·tric   also ther·mo·e·lec·tri·cal
adj.
Characteristic of, resulting from, or using electrical phenomena occurring in conjunction with a flow of heat.
 materials for batteries generating power from body heat, and photonics. Biophan has joint development and licensing agreements with Boston Scientific and NASA's Ames Center for Nanotechnology. Biophan's goal is to make all biomedical devices capable of safely and successfully working with MRI, and delivering other technologies which will improve quality of life. For more information, please visit www.biophan.com.

Cautionary Statement Regarding Forward-Looking Statements

Certain statements included in this press release may constitute forward-looking statements within the meaning of applicable securities laws. These statements reflect what Biophan anticipates, expects, or believes may happen in the future. Biophan's actual results could differ materially from the outcome or circumstance expressed or implied by such forward-looking statements as a result of a variety of factors including, but not limited to: Biophan's ability to develop its technologies; the approval of Biophan's patent applications; the successful implementation of Biophan's research and development programs; the ability of Biophan to demonstrate the effectiveness of its technology; the acceptance by the market of Biophan's technology and products incorporating such technology, the ability of Biophan to effectively negotiate and enter into contracts with medical device manufacturers for the licensing of Biophan's technology; competition; the ability of Biophan to raise capital to fund its operating and research and development activities until it generates revenues sufficient to do so; and the timing of projects and trends in future operating performance, as well as other factors expressed from time to time in Biophan's periodic filings with the Securities and Exchange Commission (the "SEC"). As a result, this press release should be read in conjunction with Biophan's periodic filings with the SEC which are incorporated herein by reference. The forward-looking statements contained herein are made only as of the date of this press release, and Biophan undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances.
COPYRIGHT 2005 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2005, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Sep 23, 2005
Words:1040
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