Bioderm Research obtains United States patent.Bioderm Research (Scottsdale, AZ) has patented Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure. The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase transaminase /trans·am·i·nase/ (-am´i-nas) aminotransferase. trans·am·i·nase n. See aminotransferase. , Phenylalanine Transaminase, Tyrosinase Tyrosinase An enzyme in a pigment cell which helps change tyrosine to DOPA during the process of making melanin. Mentioned in: Albinism tyrosinase an enzyme important in the production of melanin from tyrosine. , various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase lyase /ly·ase/ (li´as) any of a class of enzymes that remove groups from their substrates (other than by hydrolysis or oxidation), leaving double bonds, or that conversely add groups to double bonds. . These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging an·ti·ag·ing adj. Used to delay or lessen the effects of aging, especially on the skin. , collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control. (US 7,427,690) |
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