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Biocare and Epitomics announce a strategic alliance for use of rabbit monoclonal antibody technology.


Epitomics, Inc. (Burlingame, CA) and Biocare Medical LLC (Logical Link Control) See "LANs" under data link protocol.

LLC - Logical Link Control
 (Concord, CA) announced a strategic alliance to develop unique reagent products for the immunohistochemistry (IHC IHC Immunohistochemistry
IHC Intermountain Health Care
IHC Inner Hair Cells
IHC International Harvester Company
IHC Internet Healthcare Coalition
IHC Indian Head Cent
IHC Interactive Health Communication
IHC International Hurricane Center
) clinical diagnostic market. This multi-year agreement would allow Biocare to utilize Epitomics' novel rabbit monoclonal antibody (RabMab) technology platform to develop reagents and reagent test kits for the IHC diagnostic market. Epitomics will supply the rabbit monoclonal antibodies to Biocare while Biocare will utilize its expertise in the IHC market to develop a line of unique test kits incorporating single, double and triple stains. These tests will help address the pressing clinical challenge of assessing which patients should receive specific genetically targeted therapeutic agents.

Dr. Guo-Liang Yu, CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  and President of Epitomics, stated, "We are very pleased to be working with Biocare to develop new and unique products for the IHC markets. The alliance demonstrates the continued adoption of Epitomics' technology by diagnostic, pharmaceutical and biotechnology industry leaders. We are pleased to be at the forefront of the development of new diagnostic tools to aid the pathologist in therapy selection. The advantages of RabMab's for diagnostic applications include their ultra-high affinity, diverse epitope epitope: see immunity.  recognition and improved immune response to small epitopes."

Roy Paxton Yih, CEO and Director of Sales and Marketing of Biocare said, "We are very excited about the synergistic opportunities in working with Epitomics. Biocare has pioneered a 4-step double stain technology, utilizing mouse and rabbit antibodies. It uses two distinct targets in a cocktail format as well as a detection cocktail of anti-mouse, anti-rabbit conjugated conjugated
adj.
Conjugate.


estrogens, conjugated Warning - Hazardous drug!

C.E.S.
 to polymer-Horseradish peroxidase peroxidase /per·ox·i·dase/ (per-ok´si-das) any of a group of iron-porphyrin enzymes that catalyze the oxidation of some organic substrates in the presence of hydrogen peroxide.

per·ox·i·dase
n.
 and/or polymer-Alkaline phosphatase phosphatase /phos·pha·tase/ (-tas) any of a group of enzymes that catalyze the hydrolytic cleavage of inorganic phosphate from esters.

phos·pha·tase
n.
. This patent pending product system simplifies a previously cumbersome, technically complicated process. Our Double Vision Line of double-stain detection products is used in laboratories either manually on the bench or on several automation platforms that are currently commercially available. Please visit our website for a complete listing. Biocare will develop novel double and triple stain combinations incorporating Rabbit monoclonals developed by Epitomics. These products will have both research and clinical utility. Please see our web site for a complete listing of our products."

RabMab technology is used for the discovery and development of monoclonal antibodies to diagnose and treat cancer and other diseases. Compared to currently available antibody technology on the market, such as mouse hybridomas, Epitomics' technology can generate antibodies with superior binding affinity and bioactivity bi·o·ac·tiv·i·ty
n.
The effect of a given agent, such as a vaccine, upon a living organism or on living tissue.
 in a wide variety of biological assays. The high throughput and robust nature of the technology allows for the simultaneous discovery of disease targets and potential therapeutic antibodies in the same experiments, significantly shortening the drug discovery and development cycle.

Biocare is a leading provider of reagents, test kits automated equipment and special stains for the immunohistochemistry, research and other diagnostic markets. The company's core strength is its unsurpassed team of experts in the IHC and special stains market. The company provides the most innovative IHC product line that solves staining issues and vastly improves the quality of IHC stains. In addition, Biocare provides a proprietary line of equipment to meet the customer's needs for decloaking and slide staining, including the company's Nemesis line of autostainers.

Epitomics is an emerging biotechnology company that is dedicated to developing breakthrough monoclonal antibody technology for research, diagnostic and therapeutic applications. The company utilizes a unique and proprietary technology invented by scientists at Loyola University of Chicago Loyola University of Chicago, at Chicago; Jesuit; coeducational; est. 1870 as St. Ignatius College, present name adopted 1909. It has a liberal arts college and a graduate school, as well as schools of medicine, dentistry, nursing, social work, law, business  and the University of California The University of California has a combined student body of more than 191,000 students, over 1,340,000 living alumni, and a combined systemwide and campus endowment of just over $7.3 billion (8th largest in the United States).  at San Francisco. Compared to currently available antibody technology on the market, such as mouse hybridoma hybridoma /hy·brid·o·ma/ (hi?brid-o´mah) a somatic cell hybrid formed by fusion of normal lymphocytes and tumor cells.

hy·brid·o·ma
n.
, the company's proprietary technology can generate RabMAbs more efficiently and that have superior binding affinity and bioactivity in a wide variety of biological assays.

Epitomics, Inc.

+1-650-583-6688

www.epitomics.com
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Publication:BIOTECH Patent News
Date:Jan 1, 2006
Words:599
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