BioTrove and Schering-Plough Research Institute Expand RapidFire(TM) Lead Discovery Collaboration.WOBURN, Mass. -- Today BioTrove announced an expansion of its collaboration with Schering-Plough Research Institute, the research arm of Schering-Plough Corporation. As part of the ongoing relationship, BioTrove will use its proprietary RapidFire(TM) Lead Discovery service for assay development and high throughput screening on an undisclosed number of targets identified by Schering-Plough. RapidFire Lead Discovery is a mass spectrometry-based technology that enables the high throughput screening of biochemical assays. The use of mass spectrometry mass spectrometry or mass spectroscopy Analytic technique by which chemical substances are identified by sorting gaseous ions by mass using electric and magnetic fields. allows for label-free screening of challenging and intractable drug targets using native substrates. The system can analyze assays by mass spectrometry at throughputs of four to eight seconds per sample, providing a dramatic increase in throughput over conventional liquid chromatography-mass spectrometry Liquid chromatography-mass spectrometry (LC-MS) is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (aka HPLC) with the mass analysis capabilities of mass spectrometry. systems. "With RapidFire our collaborators have been able to pursue many drug targets that were previously inaccessible due to technical or economical difficulties," said Can "Jon" Ozbal, Ph.D., Director of the RapidFire program at BioTrove. "The ability of RapidFire to perform direct mass spectrometric spec·trom·e·ter n. A spectroscope equipped with scales for measuring wavelengths or indexes of refraction. spec quantification of native substrates and products facilitates very fast assay development by eliminating the need to synthesize To create a whole or complete unit from parts or components. See synthesis. and validate surrogate surrogate n. 1) a person acting on behalf of another or a substitute, including a woman who gives birth to a baby of a mother who is unable to carry the child. 2) a judge in some states (notably New York) responsible only for probates, estates, and adoptions. substrates or antibodies for conventional optical assays," he added. "We are pleased with the expansion of our ongoing relationship with Schering-Plough. The growing level of interest and novel findings from our pharmaceutical partners validates our unique position in the area of high throughput screening," said Alan Carter Alan Carter (born May, 1966 in Sydney, Australia) is a fictional character from the television series . He was played by Nick Tate. The chief Eagle pilot of Moonbase Alpha, he was on his fourth tour of duty on Moonbase Alpha as Chief pilot when the Moon broke away from Earth , Chief of Commercial Operations at BioTrove. Financial terms and the length of the relationship were not disclosed. About BioTrove, Inc. BioTrove, Inc. is a biotechnology platform company focused on advancing life science and drug discovery research by leveraging revolutionary micro- and nano-scale technologies. BioTrove has two core platforms: The OpenArray(TM) core technology enables applications based on a broadly applicable nano-fluidic solutions for massively parallel See MPP. , low-volume analysis of genomic, proteomic and cellular samples. RapidFire(TM) Lead Discovery, an assay development and high throughput screening service, unlocks the value of intractable drug targets. For more information, please visit www.biotrove.com. |
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