BioSpecifics and Tufts University receive a United States patent on promising wound healing technology.BioSpecifics Technologies Corporation (Lynbrook, NY; 516-593-7000) and Tufts University (Medford, MA; 617-636-3707) have developed a wound healing wound healing Physiology The repair of a wound Steps Inflammation, repair and closure, remodeling, final healing; repair of incisions may be either simple–'clean' wounds with little loss of tissue heal by 'primary intention', or 'dirty' wounds heal by technology which has promise to accelerate the healing of normal and abnormal wounds. In an announcement company the two organizations said they have been awarded United States Patent 5,851,522 for this technology -- an enzyme formulation that in laboratory tests enhances cell migration and cell growth, which are key to allowing wounds to heal. Laboratory research at Tufts University School of Medicine The Tufts University School of Medicine is one of the eight schools that comprise Tufts University. Located on the university's health sciences campus in the Chinatown district of Boston, Massachusetts, the medical school has clinical affiliations with thousands of doctors and , led by Ira Herman, PhD, professor of physiology, cell and molecular biology Cell and Molecular Biology may refer to:
col·lag·e·nase n. , which is manufactured by BioSpecifics, with the growth factor hbEGF found in the human epidermis, wounds may heal up to six times faster than those that are untreated. The human body normally remodels the wound healing response to injury by using naturally-produced enzymes, including human collagenase. Wound healing takes the form of migration, when cells crawl to cover injured tissue areas, and proliferation, when the cells divide and grow to repair the wound bed. The work performed in a Tufts University laboratory suggests that the new technology will accelerate normal wound healing by cell stimulation, as well as prove beneficial to healing chronic wounds such as bedsores Bedsores Definition Bedsores are also called decubitus ulcers, pressure ulcers, or pressure sores. These tender or inflamed patches develop when skin covering a weight-bearing part of the body is squeezed between bone and another body part, or a bed, , and diabetes-related lesions. Herman's laboratory work shows that collagenase alone is superior in stimulating wound healing to any of the growth factors tested. However, collagenase and hbEGF in combination were superior to either alone. BioSpecifics Technologies is a pharmaceutical company with a focus on wound healing and tissue remodeling remodeling /re·mod·el·ing/ (re-mod´el-ing) reorganization or renovation of an old structure. bone remodeling . It has pioneered the application of collagenase for several disease conditions, notably dermal dermal /der·mal/ (der´mal) pertaining to the dermis or to the skin. der·mal or der·mic adj. Of or relating to the skin or dermis. ulcers, pressure sores (bedsores), and second and third degree burns. BioSpecifics produces Collagenase ABC ABC in full American Broadcasting Co. Major U.S. television network. It began when the expanding national radio network NBC split into the separate Red and Blue networks in 1928. , the essential ingredient in the prescription drug prescription drug Prescription medication Pharmacology An FDA-approved drug which must, by federal law or regulation, be dispensed only pursuant to a prescription–eg, finished dose form and active ingredients subject to the provisos of the Federal Food, Drug, Collagenase Santyl sold in the United States, and under other trademarks abroad. Clinical trials are underway in the United States for the use of injectable collagenase in treating two diseases. Clinical and laboratory investigations further profiling the potential role of collagenase and its pharmacological activity in wound healing are being pursued. Tufts' School of Medicine and Sackler Graduate School of Biomedical Science are international leaders in innovative medical education and advanced research. The School of Medicine is renowned for excellence in primary care medicine, ambulatory medical teaching and special dual-degree programs in business administration, health management, public health and international relations. It is ranked among the top in the nation, affiliated with over 30 major health care facilities, such as New England Medical Center. The School of Medicine's Sackler Graduate School of Biomedical Science generates research that is consistently rated among the highest in the nation and the world in its impact on the advancement of medical science. |
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