BioSeparations Inc. Receives Phase II SBIR Grant.TUCSON, Ariz.--(BUSINESS WIRE)--May 12, 1998--BioSeparations Inc., Tuesday announced the receipt of a Phase II Small Business Innovation Research grant from the National Institutes of Health to support the continued development of the firm's investigational CFS CFS abbr. chronic fatigue syndrome CFS, n.pr See syndrome, chronic fatigue. CFS Chronic fatigue syndrome, see there (TM) (Charge Flow Separation) instrumentation for the isolation of fetal cells from maternal blood during pregnancy. The Phase II grant allows the company to expand its CFS development project to complete beta testing and future clinical trial objectives. Dr. Stephen Wachtel, chief of research, Reproductive Genetics Laboratory at the University of Tennessee The University of Tennessee (UT), sometimes called the University of Tennessee at Knoxville (UT Knoxville or UTK), is the flagship institution of the statewide land-grant University of Tennessee public university system in the American state of Tennessee. will be participating in the external validation testing. The Phase I data demonstrated that CFS can recover fetal cells from maternal circulation, and that the recovered cells can be used for prenatal diagnosis. The Phase II grant is designed to optimize the enrichment of fetal nucleated nucleated /nu·cle·at·ed/ (noo´kle-at?id) having a nucleus or nuclei. nu·cle·at·ed adj. Having a nucleus or nuclei. nucleated having a nucleus or nuclei. red blood cells Red blood cells Cells that carry hemoglobin (the molecule that transports oxygen) and help remove wastes from tissues throughout the body. Mentioned in: Bone Marrow Transplantation red blood cells and improve the system prior to commercialization. The CFS instrument is a computer-controlled fluid flow electrophoretic system with easy-to-use software that automates the instrument's function. The CFS process produces fetal cells for non-invasive prenatal diagnosis using fluorescence in situ hybridization Fluorescence in situ hybridization (FISH) A technique for diagnosing DiGeorge syndrome before birth by analyzing cells obtained by amniocentesis with DNA probes. FISH is about 95% accurate. (FISH) and polymerase chain reaction polymerase chain reaction (pŏl`ĭmərās') (PCR), laboratory process in which a particular DNA segment from a mixture of DNA chains is rapidly replicated, producing a large, readily analyzed sample of a piece of DNA; the process is (PCR PCR polymerase chain reaction. PCR abbr. polymerase chain reaction Polymerase chain reaction (PCR) ). Automated CFS processing saves time, labor and costs. BioSeparations Inc. also manufactures and markets ChromaHyb(TM), a unique line of universal fluorescence in situ hybridization (FISH) buffers compatible with DNA probes to label chromosomes for the detection of genetic abnormalities. The unique chemistry of ChromaHyb buffers is an integrated component of the proprietary instrument systems and software programs the company has under development for the isolation and visualization of rare cells. These product lines have broad application in established and emerging genetic research and diagnostics markets. For additional information contact Dr. David Sammons at 520/622-5882. CONTACT: BioSeparations Inc., Tucson Dr. David Sammons, 520/622-5882 |
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