BioCrystal, Ltd. Commercializes Novel Cell Culture Technology; BioCrystal's Innovative OptiCell(R) Simplifies and Improves Cell Culture Practices.COLUMBUS, Ohio Columbus is the capital and the largest city of the American state of Ohio. Named for explorer Christopher Columbus, the city was founded in 1812 at the confluence of the Scioto and Olentangy rivers, and assumed the functions of state capital in 1816. -- BioCrystal's OptiCell(R) is fully developed - Manufacturing processes and associated production quality standards are in place - Third party collaborations have successfully demonstrated the versatility of OptiCell for use in a broad range of applications for which traditional disposable cell culture devices are not suited. An article titled "Cell Culture Advances Enable Better Biology," in the January 1, 2006, issue of Genetic Engineering News raises issues associated with the need for better cell culture - processes that more closely model in vivo in vivo /in vi·vo/ (ve´vo) [L.] within the living body. in vi·vo adj. Within a living organism. in vivo adv. conditions, reduced contamination, devices for material storage and transfer, and turnkey media-to-cell culture packaging. OptiCell(R) addresses all of these needs. OptiCell is comprised of a hermetically her·met·ic also her·met·i·cal adj. 1. Completely sealed, especially against the escape or entry of air. 2. Impervious to outside interference or influence: sealed sterile chamber formed by two gas-permeable, transparent membranes sealed onto a microtiter plate-size plastic frame. The film permits differential O2 and CO2 exchange between the atmosphere and the internal chamber space in a ratio that is optimal for proper maintenance of the aerobic metabolism of cells, and a balanced pH in the cell culture medium. OptiCell is accessible through integrated self-sealing ports that provide a sterile fluid path to the chamber interior. OptiCell's patented design and construction make it the ideal tool for cell culture and subsequent procedures including in situ In place. When something is "in situ," it is in its original location. microscopy, time lapse studies, in situ immunocytostaining, transfections, single-cell cloning, and shipping live cells - direct from incubator incubator, apparatus for the maintenance of controlled conditions in which eggs can be hatched artificially. Incubator houses with double walls of mud, a fireroom, and several compartments each holding about 6,000 hens' eggs were developed in ancient times; the to mailer (1) An e-mail program. See e-mail program. (2) A message sent by an e-mail program. (3) A person or organization sending e-mail. to incubator. Cells are in contact with media at all times, facilitating OptiCell's use in automated cell culture practices. OptiCell offers the ability to separate and scale up a selected cell population in the same sterile environment. OptiCell is also well suited for continuous, laboratory-scale antibody production. BioCrystal will collaborate with others in developing bioreagent-coupled OptiCell products that offer the means to simplify and streamline cell culture practices. BioCrystal will feature OptiCell at the AACR AACR American Association for Cancer Research AACR Anglo-American Cataloging Rules AACR Australasian Association of Cancer Registries AACR African Armed Conflicts Resolved Meeting (Booth 1325) in Washington DC April 1-5. About BioCrystal, Ltd. Formed in 1996, BioCrystal brought together an interdisciplinary science group into a business structure committed to the development of novel products for applications in the life sciences and clinical medicine. BioCrystal has been awarded 40 patents in three technology areas: compounds and procedures for the diagnosis and treatment of cancer; cell culture practices and products (OptiCell(R)); and nanocrystalline fluorescent markers (BioPixels(R)) for intracellular intracellular /in·tra·cel·lu·lar/ (-sel´u-ler) within a cell or cells. in·tra·cel·lu·lar adj. Occurring or situated within a cell or cells. detection and analysis. Invitrogen Corporation acquired the BioPixels Business Unit in 2005. |
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