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BioBalance Announces Results of Clinical Study to be Presented at Major Scientific Meeting in New Orleans.


Business Editors/Health/Medical Writers

Digestive Disease Week 2004

NEW YORK--(BUSINESS WIRE)--May 18, 2004

The BioBalance Corp. announced that the results of a clinical study using PROBACTRIX(TM), BioBalance's novel biotherapeutic agent, will be presented tomorrow at the 2004 Digestive Disease Week (DDW DDW Digestive Disease Week
DDW Diseases of the Developing World
DDW Dimensional Data Warehouse
DDW Digital Data Warfare
DDW Darkness Does Wonders (bar slang)
DDW Data Driven Workflow
) in New Orleans.

The study, entitled The Probiotic pro·bi·ot·ic
n.
A dietary supplement containing live bacteria or yeast that supplements normal gastrointestinal flora, given especially after depletion of flora caused by infection or ingestion of an antibiotic drug.
 Agent E-Coli M17 Has a Healing Effect on Proximal Inflammation of the Small Bowel small bowel
n.
See small intestine.
, will be presented by Dr. Samuel Adler, Chief of Gastroenterology at the Bikur Cholim Hospital in Jerusalem, Israel. Using capsule endoscopy (CE) performed on patients with chronic intestinal symptoms and no known diagnosis, Dr. Adler identified 18 patients with proximal inflammation of the small intestine, also referred to as "mucosal IBD IBD
abbr.
inflammatory bowel disease


Inflammatory bowel disease (IBD)
Disease in which the lining of the intestine becomes inflamed.

Mentioned in: Amebiasis


IBD

1.
". Many of these patients had previously been labeled as having intractable Irritable Bowel Syndrome irritable bowel syndrome (IBS), condition characterized by frequently alternating constipation and diarrhea in the absence of any disease process. It is usually accompanied by abdominal pain, especially in the lower left quadrant, bloating, and flatulence. . Of the 18 patients who completed the four to six week course on PROBACTRIX, 12 patients showed a clinical response with marked reduction in abdominal symptoms and improvement in well-being. In these 12 patients, pretreatment pretreatment,
n the protocols required before beginning therapy, usually of a diagnostic nature; before treatment.

pretreatment estimate,
n See predetermination.
 CE revealed significant inflammation in the proximal small bowel. Post therapy CE showed significant improvement paralleling the observed clinical improvement.

"The results are remarkable, particularly in light of the fact that many of these patients had little or no response to conventional treatments," said Dr. Adler. He added, "While the exact number of patients with mucosal IBD is unknown, this work might suggest that it is more common than previously thought." The Company has filed U.S. and international patent applications relating to the treatment of this disease.

Digestive Disease Week (DDW) is the largest international medical conference of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy endoscopy

Examination of the body's interior through an instrument inserted into a natural opening or an incision, usually as an outpatient procedure. Endoscopes include the upper gastrointestinal endoscope (for the esophagus, stomach, and duodenum), the colonoscope (for the
 and gastrointestinal surgery. DDW showcases approximately 5,000 abstracts of clinical studies and hundreds of lectures on the latest advances in GI research, medicine and technology.

Background on IBS IBS Irritable bowel syndrome, see there  and IBD

Irritable Bowel Syndrome (IBS) is one of the most common chronic gastrointestinal conditions, affecting approximately 40 million Americans or 20% of the adult population. Symptoms range from constipation to diarrhea and are often accompanied by abdominal pain and bloating bloating Vox populi A lay term for post-prandial abdominal fullness or swelling . While IBS is responsible for half of the patient visits to gastroenterologists, only 20-30% of sufferers seek medical attention, thought to be due to the lack of effective treatment options available.

Inflammatory Bowel Disease inflammatory bowel disease
n. Abbr. IBD
Any of several incurable and debilitating diseases of the gastrointestinal tract characterized by inflammation and obstruction of parts of the intestine.
 (IBD) refers to two specific types of disease: Crohn's Disease and ulcerative colitis. Both of these diseases have different forms and are estimated to afflict more than one million Americans. Crohn's disease and ulcerative colitis are chronic digestive disorders. Their cause is unknown. Ulcerative colitis inflames the inner lining of the colon (large intestine) and the rectum. Crohn's disease may affect the lower part of the small intestine, the colon, and other parts of the digestive tract.

About The BioBalance Corporation

The BioBalance Corporation is a specialty pharmaceutical company focused on the development of novel treatments for various gastrointestinal (GI) disorders that are poorly addressed by current therapies via accelerated regulatory pathways. These disorders include Irritable Bowel Syndrome (IBS), inflammatory bowel disease and diarrhea caused by antibiotics, chemotherapy or AIDS.

BioBalance operates as a wholly owned subsidiary Wholly Owned Subsidiary

A subsidiary whose parent company owns 100% of its common stock.

Notes:
In other words, the parent company owns the company outright and there are no minority owners.
 of New York Health Care, a home healthcare company with which it merged on January 2, 2003 in a Stock Exchange Agreement. The combined entity trades on the OTC OTC

See: Over-the-counter.


OTC

See over-the-counter market (OTC).
 Pink Sheets under the symbol BBAL. Additional information is located on the company website at www. biobalancecorp.com.

SAFE HARBOR STATEMENT In addition to historical information, certain of the statements in the preceding paragraphs, particularly those anticipating future events, financial performance, business prospects and growth and operating strategies constitute forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. Such statements may be identified by words such as anticipate, believe, estimate, expect, intend, predict, hope or similar expressions. Such statements are based on management's current expectations and are subject to a number of factors and uncertainties which could cause actual results to differ materially from those described in the forward-looking statements, including, without limitation, satisfaction of approvals and conditions applicable to the transaction described above, the company's ability to implement its strategies and achieve its objectives and the risks and uncertainties described in reports filed by the company with the Securities and Exchange Commission under the Securities Exchange Act of 1934, as amended, including without limitation, cautionary statements made in New York Health Care's 2003 Annual Report on Form 10-K, its latest quarterly report on Form 10-Q and current reports on Form 8-K.
COPYRIGHT 2004 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2004, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:May 18, 2004
Words:749
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