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Bio-Reference Laboratories, Inc. Acquires Molecular and Cytogenetics Laboratory.


ELMWOOD PARK, N.J. -- Bio-Reference Laboratories, Inc. (NADSAQ: BRLI BRLI Bio Rad Laboratories Inc ) announced that it has acquired the molecular and cytogenetics cytogenetics /cy·to·ge·net·ics/ (-je-net´iks) the branch of genetics devoted to cellular constituents concerned in heredity, i.e. chromosomes.  facilities from Cancer Genetics, Inc. (CGI CGI
 in full Common Gateway Interface.

Specification by which a Web server passes data between itself and an application program. Typically, a Web user will make a request of the Web server, which in turn passes the request to a CGI application program.
) of Milford, MA for approximately $2.5M. The transaction includes the commercial diagnostic laboratory facilities and all technical personnel at the Milford, MA location. Ramana V. Tantravahi, Ph.D., will continue to direct the operations at the laboratory as Scientific Director. Bio-Reference has had a close working relationship with CGI for the past few years and has been utilizing the clinical diagnostic services diagnostic services,
n.pl the imaging and laboratory capabilities available for determining the cause of an illness.
 of CGI for most of its Chromosome Analysis chromosome analysis Genetics A procedure in which cells–usually of fetal origin are obtained, either in the 1st trimester by chorionic villus biopsy, or later in pregnancy by amniocentesis, and grown in a tissue culture, to detect major chromosome  testing and some of its other molecular testing. CGI was originally founded in 1999 by Dr. R.S.K Chaganti, a world renowned leader in cancer genetics. CGI will continue to operate as a separate and private entity focused on developing and marketing DNA probes.

Dr. Tantravahi is acknowledged as a renowned authority in the field of cytogenetics. He received his doctorate from Harvard in 1967 and his academic appointments include 8 years at the Columbia University, College of Physicians and Surgeons College of Physicians and Surgeons: see Columbia Univ. , and 17 years at Harvard Medical School Harvard Medical School (HMS) is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts. . His hospital appointments span 17 years at both Brigham's and Women Hospital in Boston and Dana-Farber Cancer Institute in Boston. He is well-published in journals and books and sits peer review for several publications and journals. He will be assisted by his long-time Lab Director, Jeannette Le, who has been closely associated with Dr. Tantravahi at Dana-Farber and CGI.

Marc D. Grodman M.D., President noted, "Genetic and molecular factors in Oncology has been well documented and Chromosomal Analysis is critical for the characterization of malignancies. CGI has a superb deserved reputation in this area and is among the nation's leading centers for these highly specialized and difficult analyses. We look forward to a continuing relationship with Dr. Chaganti and the entire CGI team in the future as they continue to develop innovative products in the field of cancer genetics. Our initiative in oncology remains a keystone to our strategic vision and bringing the best talent to Bio-Reference is a high priority... We have talked for some time about the fact that we will seek acquisitions that are both accretive and synergistic. The diagnostic laboratory services of CGI achieve both of those purposes. We have used the services of CGI for the past several years and we are extremely pleased to bring those services in house. Dr. Tantravahi is highly respected and adds to the quality and prestige of the oncology team that we have put together at Bio-Reference. With the addition of the laboratory services purchased from CGI, we now provide the full gamut of diagnostic testing Diagnostic testing
Testing performed to determine if someone is affected with a particular disease.

Mentioned in: Von Willebrand Disease
 for hematological malignancies within our own facilities. With this acquisition, we have improved our ability to grow and service a wider professional and geographical customer base and we intend to push those boundaries to the full extent possible."

About Cancer Genetics, Inc.

Cancer Genetics Inc., a private company, was founded in 1999 by Dr. R.S.K Chaganti, a world renowned leader in cancer genetics. CGI is dedicated to understanding the genetic causes of cancer and developing products and services to disease diagnosis and prognosis. CGI's primary focus is to develop and bring to market DNA probes for oncology, providing the cancer community with better tools for diagnosing and monitoring the disease status (including evaluating treatment protocol efficacy) of Lymphomas, Leukemias, Multiple Myeloma multiple myeloma

A malignant proliferation of abnormal plasma cells that populate the marrow-containing bones of the body. The affected plasma cells produce myeloma protein, a monoclonal antibody that replaces normal antibodies in the blood, thereby increasing susceptibility
, and Cervical Cancer. CGI also operates a Genomic Services Laboratory servicing the Pharmaceutical and Drug and clinical research markets, offering G-band karyotyping Karyotyping
A laboratory test used to study an individual's chromosome make-up. Chromosomes are separated from cells, stained, and arranged in order from largest to smallest so that their number and structure can be studied under a microscope.
, Spectral Karyotyping (SKY), FISH, Comparative Genomic Hybridization hybridization /hy·brid·iza·tion/ (hi?brid-i-za´shun)
1. crossbreeding; the act or process of producing hybrids.

2. molecular hybridization

3.
 (CGH CGH Comparative Genomic Hybridization
CGH Changi General Hospital (Singapore)
CGH Computer-Generated Hologram
CGH Community General Hospital (Syracuse, NY) 
), and FISH mapping to the biopharmaceutical and research communities. Website: www.cancergenetics.com

About Bio-Reference Laboratories, Inc.

The Company is the largest independent regional clinical laboratory in the Northeast and has major market positions in physician offices, nursing homes and correctional institutions. The Company is a full service clinical laboratory with specialty capability, especially in the areas of genomics, oncology, correctional health, and complimentary medicine. PSIMedica, a business unit of the Company, is a clinical knowledge management (CKM CKM Cabibbo-Kobayashi-Maskawa (quark mixing matrix)
CKM Certified Knowledge Manager (trademark of Hudson Associates Consulting, Inc.
) organization offering an array of information solutions for reducing healthcare costs and improving quality performance that are based on a flexible, scalable software analytical engine that utilizes all available source information, including claims data, enrollment data, prescription data and laboratory data. The Company provides a comprehensive connectivity solution to physicians, which includes disease management, laboratory reporting and ordering, as well as claims and eligibility processing through CareEvolve, its web-based healthcare portal.

Statements included in this release that are not historical in nature, are intended to be, and are hereby identified as "forward-looking statements". Statements looking forward in time are included in this release pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act The Private Securities Litigation Reform Act of 1995 (PSLRA) implemented several significant substantive changes affecting certain cases brought under the federal securities laws, including changes related to pleading, discovery, liability, class representation and awards fees and  of 1995. Such statements involve known and unknown risks and uncertainties that may cause the Company's actual results in future periods to be materially different from any future performance suggested herein.

www.bioreference.com
COPYRIGHT 2004 Business Wire
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Copyright 2004, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Jul 12, 2004
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