Bio-Bridge Announces Favorable Safety and Immunogenicity Results From Pre-clinical Study of Oral HIV Vaccine; Animal Studies Suggest Vaccine is Safe and Efficacious in Treatment of HIV.

OAK BROOK, Ill. -- Bio-Bridge Science, Inc. (OTCBB: BGES), a developer of vaccines with broad preventative and therapeutic applications, today announced that the Beijing Institute of Radiation Medicine has notified the Company that it has completed the planned pre-clinical safety and immunogenicity studies for Bio-Bridge's oral HIV vaccine. In early February, Bio-Bridge Science received encouraging initial results of the pre-clinical trials. Final results show no toxicity was observed in the animals orally administered with the HIV vaccine. There is no indication that vaccine DNA integrates into host genome and passes through placenta barrier. The immunogenicity study in monkeys shows that the vaccine induces HIV-1 gp41-specific serum antibodies (IgG) and intestinal and vaginal antibodies (sIgA). The sera, intestinal and vaginal washings neutralize HIV-1 primary isolate in vitro. The vaccine also induces HIV-1 Gag-specific T cells in the vaccinated monkeys.

"We are very pleased that the Beijing Institute of Radiation Medicine has reported favorable safety and immunogenicity data on our oral HIV vaccine," commented Liang Qiao, M.D., Chairman and CEO of Bio-Bridge Science. "It is a major milestone in the development of our HIV vaccine."

Based on these favorable results, the company is expected to file application for clinical trials with the Chinese FDA in the near future.

About Bio-Bridge Science:

Bio-Bridge Science is a biotechnology firm focused on the development of vaccines with broad therapeutic and preventive applications. Through its wholly owned subsidiary in Beijing, Bio-Bridge is developing a promising new HIV Vaccine that is expected to enter clinical trials this year in China. The vaccine, based on exclusive technology co-developed by CEO Liang Qiao, an associate professor at Loyola University Chicago's Strich School of Medicine, targets infection in mucosal tissues, the first type of tissue attacked by HIV. The Chinese government, mindful of the rapid expansion of AIDS in China has, through the "Green Mile Policy", acted to expedite the approval of domestically produced HIV Vaccines. Bio-Bridge Science's GMP facility will also be used to develop vaccines against cervical cancer and colon cancer under the same technology platform as the HIV vaccine.

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