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Benchmark Novartis's Performance against Key Rivals.


LYON, France -- Reportlinker.com announces that a new market research report related to the Pharmaceutical industry industry is available in its catalogue.

Novartis AG Novartis AG

Swiss pharmaceutical company. It was formed through the 1996 merger of two Swiss firms: Ciba (see Ciba-Geigy) and Sandoz, a chemical company with interests in pharmaceuticals, nutrition, and agriculture.
 company profile

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This analysis examines the historical and forecast performance for Novartis Novartis International AG (NYSE: NVS) is a multinational pharmaceutical company based in Basel, Switzerland that manufactures drugs such as diclofenac (Voltaren), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec / Glivec), cyclosporin A (Neoral /  in the ethical pharmaceutical sector. The profile encompasses global company strategy, portfolio and pipeline analysis and assessment of financial performance, with 1-6 year sales forecasts Sales forecast

A key input to a firm's financial planning process. External sales forecasts are based on historical experience, statistical analysis, and consideration of various macroeconomic factors.
 for key drugs. An interactive forecasting and analysis tool provides continually con·tin·u·al  
adj.
1. Recurring regularly or frequently: the continual need to pay the mortgage.

2.
 updated quantitative and qualitative information.

Scope

Benchmark Novartis's performance against key rivals in the ethical pharmaceutical sectorAnalyze the reasons driving Novartis's impressive forecast sales CAGR CAGR

See: Compound Annual Growth Rate
 of 7.3% over the period 2006-12Assess Novartis's late stage pipeline, the strongest within the Big Pharma peer set, which will act as the key lever lever, simple machine consisting of a bar supported at some stationary point along its length and used to overcome resistance at a second point by application of force at a third point. The stationary point of a lever is known as its fulcrum.  on company sales growth to 2012

CHAPTER 1 EXECUTIVE SUMMARY 2

Key findings 2

Historical and forecast ethical sales performance 3

Therapeutic strategy 4

Launch and expiry outlook 10

Externalization The ability to easily connect to and transfer information between business partners. Increasingly, information systems are designed to make their data available to outside partners and customers. This type of collaboration is expected to be a vital part of IT in the 21st century. See EDI. , geographic and molecule type strategies 13

Externalization strategy 14

Geographic strategy 15

Molecule type strategy 15

SWOT analysis SWOT Analysis

A tool that identifies the strengths, weaknesses, opportunities and threats of an organization.
 16

Strengths 17

Weaknesses 18

Opportunities 20

Threats 21

Sandoz For the pre-1996 company, see .

Sandoz is the generics subsidiary of Novartis, a multinational pharmaceutical company. The company develops, manufactures and markets off-patent medicines as well as pharmaceutical and biotechnological active ingredients.
 sales growth contribution 21

CHAPTER 2 CORPORATE HISTORY 27

Key findings 27

Background 28

Key corporate developments 28

M&A history 29

Shareholding in Roche 30

Other M&A 31

Sandoz 31

Chiron 32

Rationale rationale (rash´nal´),
n the fundamental reasons used as the basis for a decision or action.
 33

Long-term Long-term

Three or more years. In the context of accounting, more than 1 year.


long-term

1. Of or relating to a gain or loss in the value of a security that has been held over a specific length of time. Compare short-term.
 growth ensured? 33

Resolving Chiron's historical manufacturing problem 34

CHAPTER 3 HISTORICAL PERFORMANCE 35

Key findings 35

Introduction 36

Revenue and growth rate analysis, 2001-06 36

Revenue and growth rate vs. peer set 37

Product analysis, 2001-06 39

Growth drivers 39

Glivec 39

Diovan Di·o·van

A trademark for the drug valsartan.


valsartan

Diovan

Pharmacologic class: Angiotensin II receptor antagonist

Therapeutic class: Antihypertensive

 40

Zometa 40

Co-Diovan 40

Femara Fe·mar·a

A trademark for the drug letrozole.


letrozole Warning - Hazardous drug!

Femara

Pharmacologic class: Aromatase inhibitor

 40

Operating revenue operating revenue

Revenue from any regular source. Revenue from sales is adjusted for discounts and returns when calculating operating revenue. Compare other revenue.
 and cost analysis, 2001-06 41

Operating revenue/cost analysis 43

CHAPTER 4 FORECAST PERFORMANCE 45

Key findings 45

Introduction 46

Revenue and growth rate, 2006-12 46

Product analysis, 2006-12 48

Growth drivers 53

Glivec 53

Aclasta 54

Tekturna 54

Lucentis 55

Exjade 55

Growth resistors 55

Lotrel 55

Lamisil Lamisil Terbinafine Dermatology An antifungal for tinea pedis, tinea cruris, tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, T rubrum, fluconazole-resistant oral candidiasis. See Fluconazole.  56

Trileptal 56

Therapy area analysis, 2006-12 58

Oncology oncology /on·col·o·gy/ (ong-kol´ah-je) the sum of knowledge regarding tumors; the study of tumors.

on·col·o·gy
n.
 61

Other 62

Infectious disease Infectious disease

A pathological condition spread among biological species. Infectious diseases, although varied in their effects, are always associated with viruses, bacteria, fungi, protozoa, multicellular parasites and aberrant proteins known as prions.
 62

Musculosketal 62

Gastroenterology gastroenterology

Medical specialty dealing with digestion and the digestive system. In the 17th century Jan Baptista van Helmont conducted the first scientific studies in the field; William Beaumont published his own observations in 1833.
 62

Therapy area focus 63

Cardiovascular cardiovascular /car·dio·vas·cu·lar/ (-vas´ku-ler) pertaining to the heart and blood vessels.

car·di·o·vas·cu·lar
adj.
Abbr.
 & hematology hematology

Branch of medicine concerned with the nature, function, and diseases of the blood. It covers the cellular and serum composition of blood, the coagulation process, blood-cell formation, hemoglobin synthesis, and disorders of all these.
 65

Oncology 66

Musculoskeletal musculoskeletal /mus·cu·lo·skel·e·tal/ (-skel´e-t'l) pertaining to or comprising the skeleton and muscles.

mus·cu·lo·skel·e·tal
adj.
Relating to or involving the muscles and the skeleton.
 68

Launches and expiries analysis, 2006-12 71

Launch portfolio 71

Core portfolio 74

Expiry portfolio 76

Launch/core/expiry configuration 77

Externalization analysis, 2006-12 81

Geographic analysis, 2006-12 86

Molecule type analysis, 2006-12 90

CHAPTER 5 KEY PRODUCTS AND COMPETITORS 95

Key findings 95

Overview 96

Oncology 97

Gleevec/Glivec 97

Overview 97

Sales forecast 98

News flow 98

Femara 102

Overview 102

Sales forecast 103

News flow 103

Cardiovascular 106

Diovan/Co-Diovan 106

Overview 106

Sales forecast 107

News flow 108

Exforge 113

Overview 113

Sales forecast 114

News flow 115

Tekturna 117

Overview 117

Sales forecast 118

News flow 118

Galvus 122

Overview 122

Sales forecast 123

News flow 123

Lotrel 127

Overview 127

Sales forecast 128

News flow 128

Lescol Les·col

A trademark for the drug fluvastatin.


fluvastatin sodium

Lescol, Lescol XL

Pharmacologic class: HMG-CoA reductase inhibitor

Therapeutic class: Antihyperlipidemic
 130

Overview 130

Sales forecast 131

News flow 131

Musculoskeletal 134

Aclasta/Reclast 134

Overview 134

Sales forecast 135

News flow 136

Infectious diseases infectious diseases: see communicable diseases.  139

Lamisil 139

Overview 139

Sales forecast 140

News flow 140

CNS See Continuous net settlement.

CNS

See continuous net settlement (CNS).
 142

FTY FTY Failure to Yield (law enforcement)
FTY First Time Yield
FTY Fulton County Airport-Brown Field Airport (Atlanta, GA) 
720 142

Overview 142

Sales forecast 143

News flow 143

Trileptal 146

Overview 146

Sales forecast 147

News flow 147

Other 149

Exjade 149

Overview 149

Sales forecast 150

News flow 150

Lucentis 152

Overview 152

Sales forecast 153

News flow 154

R&D pipeline 157

CHAPTER 6 APPENDIX 159

IMS (1) See IP Multimedia Subsystem.

(2) (Information Management System) An early IBM hierarchical DBMS for IBM mainframes. IMS was widely implemented throughout the 1970s under MVS and continues to be used under z/OS.
 vs. company-reported data reconciliation 159

References 162

Abbreviations 163

List of Tables

Table 1: Peer set overview 37

Table 2: Operating revenue/cost analysis ($m), 2001-06 41

Table 3: Operating cost ratio analysis (% of total revenues), 2001-06 43

Table 4: Product portfolio overview, sales ($m), 2006-12 48

Table 5: Therapy area overview, sales ($m), 2006-12 58

Table 6: Launch portfolio overview, sales ($m), 2006-12 72

Table 7: Core portfolio overview, sales ($m), 2006-12 74

Table 8: Expiry portfolio overview, sales ($m), 2006-12 76

Table 9: Externally developed portfolio ($m), 2006-12 81

Table 10: Molecule type overview, sales ($m), 2006-12 90

Table 11: Key products overview 96

Table 12: Gleevec/Glivec: overview 97

Table 13: Gleevec/Glivec: sales forecast ($m), 2006-12 98

Table 14: Gleevec/Glivec: news flow 98

Table 15: Femara: overview 102

Table 16: Femara: sales forecast ($m), 2006-12 103

Table 17: Femara: news flow 103

Table 18: Diovan/Co-Diovan: overview 106

Table 19: Diovan: sales forecast ($m), 2006-12 107

Table 20: Co-Diovan: sales forecast ($m), 2006-12 107

Table 21: Diovan/Co-Diovan: news flow 108

Table 22: Exforge: overview 113

Table 23: Exforge: sales forecast ($m), 2006-12 114

Table 24: Exforge: news flow 115

Table 25: Tekturna: overview 117

Table 26: Tekturna: sales forecast ($m), 2006-12 118

Table 27: Tekturna: news flow 118

Table 28: Galvus: overview 122

Table 29: Galvus: sales forecast ($m), 2006-12 123

Table 30: Galvus: news flow 123

Table 31: Lotrel: overview 127

Table 32: Lotrel: sales forecast ($m), 2006-12 128

Table 33: Lotrel: news flow 128

Table 34: Lescol: overview 130

Table 35: Lescol: sales forecast ($m), 2006-12 131

Table 36: Lescol: news flow 131

Table 37: Aclasta/Reclast: overview 134

Table 38: Aclasta: sales forecast ($m), 2006-12 135

Table 39: Aclasta/Reclast: news flow 136

Table 40: Lamisil: overview 139

Table 41: Lamisil: sales forecast ($m), 2006-12 140

Table 42: Lamisil: news flow 140

Table 43: FTY720: overview 142

Table 44: FTY720: sales forecast ($m), 2006-12 143

Table 45: FTY720: news flow 143

Table 46: Trileptal: overview 146

Table 47: Trileptal: sales forecast ($m), 2006-12 147

Table 48: Trileptal: news flow 147

Table 49: Exjade: overview 149

Table 50: Exjade: sales forecast ($m), 2006-12 150

Table 51: Exjade: news flow 150

Table 52: Lucentis: overview 152

Table 53: Lucentis: sales forecast ($m), 2006-12 153

Table 54: Lucentis: news flow 154

Table 55: Novartis's R&D pipeline 157

List of Figures

Figure 1: Historical and forecast ethical sales performance (% CAGR), Novartis and Big Pharma peer set 3

Figure 2: Therapeutic focus vs. Big Pharma peer set (%), 2006 5

Figure 3: Launch, core and expiry, absolute sales growth, 2006-12 (sales as % of 2006 sales), Novartis 11

Figure 4: Launch, core and expiry, absolute sales growth, 2006-12 (sales as % of 2006 sales), peer set 12

Figure 5: Molecule type, externalization and geographic market dependency dependency

In international relations, a weak state dominated by or under the jurisdiction of a more powerful state but not formally annexed by it. Examples include American Samoa (U.S.) and Greenland (Denmark).
 (%) vs. peer set, 2006 13

Figure 6: Molecule type, externalization and geographic market dependency (%) vs. peer set, 2012 14

Figure 7: SWOT analysis of Novartis 16

Figure 8: Novartis Ethical Pharmaceuticals/Sandoz sales contribution, 2006-12 (% of 2006 sales) 22

Figure 9: Recent M&A history/corporate structure 29

Figure 10: Revenue & growth rate (ethical sales) ($m), 2001-06 36

Figure 11: Ethical revenue ($m) and growth rate (%) vs. peer set, 2001-06 38

Figure 12: Growth drivers/resistor products of historical revenue performance ($m), 2001-06 39

Figure 13: Operating revenue/cost analysis ($m), 2001-06 42

Figure 14: Operating cost ratio analysis (% of total revenues), 2001-06 44

Figure 15: Ethical revenue ($m) and growth rate (%), 2006-12 46

Figure 16: Top five products by sales ($m), 2006 51

Figure 17: Top five products by sales ($m), 2012 52

Figure 18: Growth drivers and resistors by product, 2006-12 53

Figure 19: Key strategic products, sales ($m), 2006-12 57

Figure 20: Ethical sales by therapy area ($m), 2006-12 60

Figure 21: Growth drivers and resistors by therapy area ($m), 2006-12 61

Figure 22: Ethical sales by therapy area (%), 2006-12 63

Figure 23: Therapy area focus compared with peer set (% total ethical sales), 2006 64

Figure 24: Therapy area focus compared with peer set (% total ethical sales), 2012 69

Figure 25: Launch schedule, sales ($m), 2006-12 73

Figure 26: Core products sales growth ($m), 2006-12 75

Figure 27: Expiry schedule, sales ($m), 2006-12 77

Figure 28: Launch, core and expiry, sales ($m), 2006-12 78

Figure 29: Launch, core and expiry, absolute sales growth, 2006-12 (sales as % of 2006 sales), Novartis 79

Figure 30: Launch, core and expiry, absolute sales growth, 2006-12 (sales as % of 2006 sales), peer set 80

Figure 31: Externalization dependency, sales ($m), 2006-12 82

Figure 32: Growth drivers and resistors, externally vs. internally discovered products, sales ($m), 2006-12 83

Figure 33: Externalization dependency vs. peer set, % total sales, 2006 84

Figure 34: Externalization dependency vs. peer set, % total sales, 2012 85

Figure 35: Geographical sales breakdown ($m), 2006-12 86

Figure 36: Growth drivers and resistors by geography, sales ($m), 2006-12 87

Figure 37: US dependency vs. peer set, % total sales, 2006 88

Figure 38: US dependency vs. peer set, % total sales, 2012 89

Figure 39: Growth drivers and resistors by molecule type, sales ($m), 2006-12 91

Figure 40: Molecule type sales breakdown ($m), 2006-12 92

Figure 41: Biologics dependency vs. peer set, % total sales, 2006 93

Figure 42: Biologics dependency vs. peer set, % total sales, 2012 94

Figure 43: IMS vs. company-reported ethical sales discrepancy DISCREPANCY. A difference between one thing and another, between one writing and another; a variance. (q.v.)
     2. Discrepancies are material and immaterial.
 ($m), 2006 160

Figure 44: IMS vs. company-reported ethical sales forecast growth rates Growth Rates

The compounded annualized rate of growth of a company's revenues, earnings, dividends, or other figures.

Notes:
Remember, historically high growth rates don't always mean a high rate of growth looking into the future.
 (%), 2006-12 161

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Date:Nov 29, 2007
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