Bayer HealthCare Licenses BIOBASE's BRENDA(R)-AMENDA(TM) Database for Target Research.WOLFENBUETTEL, Germany -- BIOBASE announced today the signing of the BRENDA-AMENDA license agreement with the Bayer subgroup Bayer HealthCare. This license provides researchers at the Bayer HealthCare Institute for Target Research in Wuppertal, Germany with access to this expert-maintained database that summarizes more than fifty years of enzyme and metabolism research. "We are very proud that a leading company such as Bayer HealthCare has selected the most comprehensive enzyme information system available, BRENDA-AMENDA, as an indispensable resource for target-based research for cardiovascular diseases," states Prof. Dr. Edgar Wingender, President and CSO (Chief Security Officer) The person in charge of all staff members who are responsible for promulgating, enforcing and administering security policies for all systems within an enterprise or division. of BIOBASE. "BRENDA-AMENDA includes a customer-oriented enhancement of the BRENDA database, with special text mining features that are well-suited for industrial applications," adds Prof. Dietmar Schomburg (University of Cologne The University of Cologne (German Universität zu Köln) is one of the oldest universities in Europe and, with over 44,000 students, the largest university in Germany. , Germany), who has led the development of BRENDA since 1987 and continues with it today at enzymeta GmbH, Cologne, Germany. "The new text-mining based AMENDA module, which has been available since June of 2006, expands BRENDA's enzyme-related reference content by 5-fold by means of structured access to organism-specific enzyme information, such as statements about tissue affiliation or sub-cellular localization Customizing software and documentation for a particular country. It includes the translation of menus and messages into the native spoken language as well as changes in the user interface to accommodate different alphabets and culture. See internationalization and l10n. , from 15 million PubMed articles." Time-saving literature reviews with BRENDA-AMENDA BRENDA-AMENDA is a relational database relational database Database in which all data are represented in tabular form. The description of a particular entity is provided by the set of its attribute values, stored as one row or record of the table, called a tuple. that contains manually-curated biochemical and molecular information about more than 83,000 enzymes from 9,800 organisms, which correspond to the current EC system of the International Union of Biochemistry and Molecular Biology The International Union of Biochemistry and Molecular Biology (IUBMB) is an international non-governmental organisation concerned with biochemistry and molecular biology. Formed in 1955 as the International Union of Biochemistry, the union had 72 member countries in 2005. (IUBMB IUBMB International Union of Biochemistry and Molecular Biology ). To date, BRENDA-AMENDA contains 500,000 enzyme-ligand correlations, including more than 46,000 different chemical compounds that act as ligands and 34,500 ligand structures. A user-friendly interface and powerful search capabilities make it possible to carry out time-saving literature reviews of more than 56,600 publications. Currently, 19 international biotech companies use BRENDA-AMENDA for their research activities. Academic users can register for complimentary access to BRENDA at www.brenda-enzymes.org. BIOBASE (www.biobase-international.com), based in Wolfenbottel (Germany), with branch offices in Beverly, MA (USA) and Bangalore (India) is a leading provider of expertly curated biological databases for the life science industry. BIOBASE's product portfolio, referred as the BIOBASE Knowledge Library (BKL BKL Burke Lakefront Airport, Cleveland, Ohio (Airport Code) BKL Big Kernel Lock ), includes industry standards such as TRANSFAC([R]), TRANSPATH([R]), YPD YPD Yeast Peptone Dextrose (media for growing yeast) YPD Young People's Division YPD Floating Pile Driver (Non Self-Propelled) YPD Yonkers Police Department [TM]and HumanPSD[TM] databases. In combination BIOBASE's powerful systems biology Systems biology, a field of study in the biosciences, focuses on the systematic study of complex interactions in biological systems. Particularly from 2000 onwards, the term is used widely in the biosciences, and in a variety of contexts. tool, ExPlain[TM], the BKL can be used to analyze complex regulatory networks and identify key molecules linked to human disease. In addition to the BKL, BIOBASE provides a growing collection of third-party databases including BRENDA([R]) and Human Gene Mutation Database (HGMD HGMD Human Gene Mutation Database HGMD Hybrid Genetic Multiuser Detector ([R])). More than 600 customers now license BIOBASE databases. Bayer HealthCare, a subsidiary of Bayer AG, is one of the world's leading, innovative companies in the healthcare and medical products industry and is based in Leverkusen, Germany. Bayer HealthCare generated sales amounting to some 9.4 billion euros and employed 33.800 people worldwide in 2005. The company combines the global activities of the Animal Health, Consumer Care, Diabetes Care, Diagnostics and Pharmaceuticals divisions. The new Pharmaceuticals division was established on January 1, 2006, and comprises the former Biological Products and Pharmaceutical divisions. Pharmaceuticals now has three business units: Hematology/Cardiology, Oncology and Primary Care. Bayer HealthCare's aim is to discover and manufacture products that will improve human and animal health worldwide. The products enhance well-being and quality of life by diagnosing, preventing and treating diseases. |
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