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Battelle Pulmonary Therapeutics Signs Development and Manufacturing Agreement with Cardinal Health's Sterile Technology Group.


Business Editors & Health/Medical Writers

BIOWIRE2K

COLUMBUS, Ohio--(BW HealthWire)--March 5, 2002

Battelle Pulmonary Therapeutics Inc. (BPT BPT Bridgeport (Connecticut)
BPT Best Practicable Control Technology
BPT Best Practicable Control Technology Currently Available
BPT BP Prudhoe Bay Royalty Trust (stock symbol)
BPT Boston Playwrights' Theatre
) today announced it has signed an agreement with Cardinal Health's Sterile Technology Group to provide sterile development and manufacturing services for BPT's Mystic(TM) inhalation device. A division of Cardinal Health's Pharmaceutical Technologies & Services, the Sterile Technologies Group will collaborate with BPT to design the sterile pouch and manufacturing process that holds the liquid pharmaceutical inside its Mystic inhalation device.

Cardinal Health <includeonly></includeonly>

Cardinal Health (NYSE: CAH) is a premier, global healthcare company dedicated to making healthcare safer and more productive. Overview
Headquartered in Dublin, Ohio, Cardinal Health, Inc.
 will work with BPT to design this component and process, making effective pulmonary drug delivery possible regardless of how the patient holds the inhaler inhaler /in·hal·er/ (in-hal´er)
1. an apparatus for administering vapor or volatilized medications by inhalation.

2. ventilator (2).


in·hal·er
n.
 -- a subtle yet critical consideration with certain self-administered medications. Cardinal Health's proprietary technologies will be used in multiple applications of the Mystic inhalation device.

BPT's proprietary Mystic drug delivery technology offers precise selection and control of particle size Particle size, also called grain size, refers to the diameter of individual grains of sediment, or the lithified particles in clastic rocks. The term may also be applied to other granular materials. , highly reproducible dosing, and targeted deposition in the lungs to concentrate drugs where they are needed. The inhaler's technical performance is far superior to currently available metered-dose inhalers, dry powder inhalers The Dry Powder Inhaler is generally a proprietary device to deliver medications for the treatment or maintenance management of respiratory diseases and conditions. These conditions or diseases may include Asthma, Bronchitis, Emphysema, COPD and Diabetes.  and other new generation inhalers in development. BPT has licensed the technology to several leading pharmaceutical companies to develop therapies to treat asthma, chronic obstructive pulmonary disease chronic obstructive pulmonary disease
n. Abbr. COPD
A chronic lung disease, such as asthma or emphysema, in which breathing becomes slowed or forced.
 and respiratory infections.

"The addition of Cardinal Health as our sterile pharmaceutical manufacturer is a significant step toward the realization of our complete manufacturing strategy," said William C. Zimlich, vice president of device product development for BPT. "Cardinal Health Pharmaceutical Technologies & Services is recognized as a world-class service provider. Our combined expertise and resources will be instrumental in allowing us to position our Mystic technology as the pulmonary delivery technology of choice in the pharmaceutical industry."

"As a leader in the production of sterile liquid pharmaceuticals, Cardinal Health Sterile Technologies Group is a vital partner in the development and manufacture of new medicines," said Frank Leo Leo, in astronomy
Leo [Lat.,=the lion], northern constellation lying S of Ursa Major and on the ecliptic (apparent path of the sun through the heavens) between Cancer and Virgo; it is one of the constellations of the zodiac.
, president. "This agreement supports our mission to provide innovations in healthcare and we anticipate a long and successful relationship with Battelle Pulmonary Therapeutics."

About Cardinal Health Pharmaceutical Technologies & Services

As one of Cardinal Health's four main business segments, PTS PTS

put to sleep; a common euphemism for euthanasia, but also used to describe general anesthesia.
 provides services to the makers of pharmaceutical and biotechnology products through a broad spectrum of complementary services including unique drug delivery systems and related manufacturing capabilities. PTS is a leading provider of contract manufacturing and packaging of oral and sterile liquid pharmaceuticals and other health-care products in topical, inhaled in·hale  
v. in·haled, in·hal·ing, in·hales

v.tr.
1. To draw (air or smoke, for example) into the lungs by breathing; inspire.

2.
 and ophthalmic formulations, as well as providing contract drug development and sale services to pharmaceutical companies. It is also a leading provider of diversified clinical and commercial packaging services in both the United States United States, officially United States of America, republic (2005 est. pop. 295,734,000), 3,539,227 sq mi (9,166,598 sq km), North America. The United States is the world's third largest country in population and the fourth largest country in area.  and Europe.

About Cardinal Health

Cardinal Health, Inc. (www.cardinal.com) is a leading provider of products and services supporting the health-care industry. Cardinal companies develop, manufacture, package and market products for patient care; develop drug-delivery technologies; distribute pharmaceuticals, medical-surgical and laboratory supplies; and offer consulting and other services that improve quality and efficiency in health care. The company employs more than 49,000 people on five continents and produces annual revenues of more than $40 billion.

About Battelle Pulmonary Therapeutics Inc.

Battelle Pulmonary Therapeutics is a pre-public specialty pharmaceutical company leveraging science and engineering to design more effective medicines. The company has a growing portfolio of ten products in development, with several in early clinical trials. The products are based on three proprietary platforms: Mystic(TM) inhalation technology, novel formulation technologies, and inhaled anticancer therapy. The company develops products by combining these platforms with novel or generic compounds to create therapies to treat respiratory and systemic diseases and lung cancer lung cancer, cancer that originates in the tissues of the lungs. Lung cancer is the leading cause of cancer death in the United States in both men and women. Like other cancers, lung cancer occurs after repeated insults to the genetic material of the cell. . BPT has partnerships with numerous pharmaceutical corporations, including Abbott, GlaxoSmithKline and Pfizer and is a subsidiary of Battelle Memorial Institute The Battelle Memorial Institute is a private not-for-profit applied science and technology development company headquartered in Columbus, Ohio. The institute opened in 1929 but traces its origins to the 1923 will of Ohio industrialist Gordon Battelle which provided for its , the world's largest independent and private research and development organization. For more information on BPT, reference the company's website at www.bpt-inc.com.
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