BIOQUAL Announces Award of a Small Business Innovation Research -- SBIR -- Phase II Grant On Comparative DNA Sequence Variation in Alzheimer Genes for $738,847.Business Editors/Health & Medical Writers ROCKVILLE, Md.--(BUSINESS WIRE)--Sept. 27, 2001 BIOQUAL, Inc. (BIOQ, OTC-BB; BQI BQI Backward Quality Indication BQI Better Quality Information , Chicago Stock Exchange Chicago Stock Exchange (CHX) A major exchange trading only stocks, with 90% of trades taking place on an automated execution system, called MAX. ) has been awarded a two-year Phase II SBIR SBIR Small Business Innovation Research (program/grant) SBIR Space Based Infra-Red SBIR Speaker-Boundary Interference SBIR Site Backsurface-referenced Ideal Plane/Range (silicon wafers) grant, effective September 30, 2001, entitled "Comparative DNA Sequence DNA sequence Genetics The precise order of bases–A,T,G,C–in a segment of DNA, gene, chromosome, or an entire genome. See Base pair, Base sequence analysis, Chromosome, Gene, Genome. Variation In Alzheimer Genes" for $738,847. Chimpanzees are humankind's closest evolutionary relatives and have much higher levels of genetic variation, as compared to humans. These facts previously allowed BIOQUAL scientists to identify DNA DNA: see nucleic acid. DNA or deoxyribonucleic acid One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes. mutations in Alzheimer Disease (AD)-related genes in chimpanzees. However, it is not known for certain whether chimpanzees actually suffer from AD. BIOQUAL scientists will use biochemical assays to identify aged, living chimpanzees with dementia or other aging-related disorders. BIOQUAL scientists will then search for disease-causing mutations in those individuals, as well as in archival chimpanzee chimpanzee, an ape, genus Pan, of the equatorial forests of central and W Africa. The common chimpanzee, Pan troglodytes, lives N of the Congo River. Full-grown animals of this species are up to 5 ft (1. brain tissues having AD-related neuropathology neuropathology /neu·ro·pa·thol·o·gy/ (-pah-thol´ah-je) pathology of diseases of the nervous system. neu·ro·pa·thol·o·gy n. The study of diseases of the nervous system. , at five AD-related genes. The characterization of genetic mutations in chimpanzees will broaden our understanding of the evolution of this increasingly common human disease and help determine whether chimpanzees really do suffer from AD and, if not, it will help to understand the genetic reasons why they do not suffer from AD. This knowledge could facilitate the identification of new pharmaceuticals for the treatment of AD in both humans and chimpanzees. Statements herein that are not descriptions of historical facts are forward-looking and subject to risk and uncertainties. Actual results could differ materially from those currently anticipated due to a number of factors including those set forth in BIOQUAL's Securities and Exchange Commission filings under "Risk Factors", including risks relating to the early stage of products under development; uncertainties relating to clinical trials; dependence on third parties; future capital needs; the ability to continue to extend its government contracts and obtain new contracts; and risks relating to the commercialization, if any, of BIOQUAL's proposed products (such as marketing, safety, regulatory, patent, product liability, supply competition, and other risks). www.bioqual.com |
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