BIOQUAL Announces Award for Alzheimer's Disease Research Small Business Innovation Research --SBIR-- Grant From the National Institutes of Health.Business Editors/Health & Medical Writers ROCKVILLE, Md.--(BUSINESS WIRE)--March 2, 2000 BIOQUAL, Inc. (BIOQ-OTC, BQI-Chicago Stock Exchange) announced today that it had been awarded a $99,153 Phase I grant from the National Institutes of Health (NIH "Not invented here." See digispeak. NIH - The United States National Institutes of Health. ) as part of its Small Business Innovation Research (SBIR SBIR Small Business Innovation Research (program/grant) SBIR Space Based Infra-Red SBIR Speaker-Boundary Interference SBIR Site Backsurface-referenced Ideal Plane/Range (silicon wafers) ) program. The six month grant is to identify and characterize DNA sequence DNA sequence Genetics The precise order of bases–A,T,G,C–in a segment of DNA, gene, chromosome, or an entire genome. See Base pair, Base sequence analysis, Chromosome, Gene, Genome. variation in chimpanzees at four genes that contain mutations implicated im·pli·cate tr.v. im·pli·cat·ed, im·pli·cat·ing, im·pli·cates 1. To involve or connect intimately or incriminatingly: evidence that implicates others in the plot. 2. in the pathogenesis of Alzheimer's Disease (AD). Some comparative research on AD-related genetic loci and their involvement in age-related cognitive dysfunction or neuroanatomical neu·ro·a·nat·o·my n. pl. neu·ro·a·nat·o·mies 1. The branch of anatomy that deals with the nervous system. 2. The neural structure of a body part or organ: the neuroanatomy of the eye. degeneration has been done in great apes. However, both the extent of DNA sequence variation and its role in aging-related neuropathology neuropathology /neu·ro·pa·thol·o·gy/ (-pah-thol´ah-je) pathology of diseases of the nervous system. neu·ro·pa·thol·o·gy n. The study of diseases of the nervous system. is poorly understood. Consequently, there is a need for more extensive comparative work involving population screening and DNA sequencing of the various AD related loci homologous genes in hominoid hom·i·noid adj. 1. Of or belonging to the superfamily Hominoidea, which includes apes and humans. 2. Resembling a human. n. A member of the Hominoidea. apes. This could help identify and characterize species specific mutations or conserved polymorphisms that influence cognitive or neurological degeneration. The technical ability to rapidly genotype such loci in apes that develop human-like neuritic plaques, would help characterize the role of these genes in AD; the genotypic knowledge so gained could be used to develop more useful prospective studies of AD epidemiology in humans. The correlation of neuropathologic studies with AD-related mutations can facilitate a pharmacogenomics approach to testing novel pharmaceuticals for human use. Statements herein that are not descriptions of historical facts are forward-looking and subject to risk and uncertainties. Actual results could differ materially from those currently anticipated due to a number of factors including those set forth in BIOQUAL's Securities and Exchange Commission filings under "Risk Factors", including risks relating to the early stage of products under development; uncertainties relating to clinical trials; dependence on third parties; future capital needs; and risks relating to the commercialization, if any, of BIOQUAL's proposed products (such as marketing, safety, regulatory, patent, product liability, supply competition, and other risks). |
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