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BIND Biosciences, Inc. Receives $2M NIST ATP Award to Develop a High-Throughput Platform for Targeted Nanoparticle Engineering.


CAMBRIDGE, Mass. -- BIND Biosciences, Inc. (BIND), a privately held biopharmaceutical company developing therapeutic targeted nanoparticles, announced today that it has received a three year $2,000,000 award from the U.S. National Institutes of Standards and Technology (NIST (National Institute of Standards & Technology, Washington, DC, www.nist.gov) The standards-defining agency of the U.S. government, formerly the National Bureau of Standards. It is one of three agencies that fall under the Technology Administration (www.technology. ) under its Advanced Technology Program (ATP ATP: see adenosine triphosphate.
ATP
 in full adenosine triphosphate

Organic compound, substrate in many enzyme-catalyzed reactions (see catalysis) in the cells of animals, plants, and microorganisms.
) to further develop its platform for high-throughput formulation and selection of targeted nanoparticles.

"Given the extremely rigorous technical peer review involved in this competition, this award represents an important validation of BIND's technology platform," according to Dr. Stephen Zale, Vice President of Development at BIND and Principal Investigator of BIND's ATP project. He continued, "The ATP funding will accelerate industrialization industrialization

Process of converting to a socioeconomic order in which industry is dominant. The changes that took place in Britain during the Industrial Revolution of the late 18th and 19th century led the way for the early industrializing nations of western Europe and
 of our high-throughput combinatorial platform for nanoparticle fabrication fabrication (fab´rikā´shn),
n the construction or making of a restoration.
 and screening that uniquely enables BIND to develop and manufacture targeted nanoparticle therapeutics optimized for a specific disease."

"We are delighted to have been selected by NIST for the ATP award and for their recognition of our platform's potential to create an entirely novel class of therapeutics based on optimally engineered targeted polymeric nanoparticles," said Glenn Batchelder, President and Chief Executive Officer of BIND. "We are fortunate to have Dr. Zale leading this program. Dr. Zale's two decades of pharmaceutical development experience includes a twelve year tenure at Alkermes where, as Vice President of Injectable Products, he helped build an extremely successful polymeric microparticle-based drug delivery platform which has led to the commercialization of important products such as Risperdal Consta(TM) and Vivitrol(TM)."

The NIST Advanced Technology Program selects the most promising early stage technologies with the potential to create fundamental paradigm shifts in their respective spaces. Of the hundreds of applicants for this year's ATP NIST program, less than ten percent were awarded contracts. ATP's early stage support has dramatically accelerated the development of many innovative technologies resulting in long term commercial success and delivering far reaching societal benefits.

About BIND Biosciences, Inc.

BIND Biosciences is a privately held biopharmaceutical company focused on developing therapeutic targeted nanoparticles. The company's product-platform leverages the convergence of polymeric biomaterials, nanoparticle engineering and combinatorial synthesis to uniquely enable BIND to design and optimize targeted nanoparticle therapeutics for specific indications. BIND's technology concentrates drug at the intended site of action while minimizing systemic exposure, thereby improving efficacy and reducing off-target effects. The company's platform is broadly applicable across therapeutic areas with the initial product development efforts focused in cancer and cardiovascular disease Cardiovascular disease
Disease that affects the heart and blood vessels.

Mentioned in: Lipoproteins Test

cardiovascular disease 
. The company anticipates initiating clinical trials for their first product in 2009.

BIND was founded in 2006 by two pioneers in the field of therapeutic targeted nanoparticles, Dr. Robert Langer, MIT MIT - Massachusetts Institute of Technology  Institute Professor, and Dr. Omid Farokhzad, Harvard Medical School Harvard Medical School (HMS) is one of the graduate schools of Harvard University. It is a prestigious American medical school located in the Longwood Medical Area of the Mission Hill neighborhood of Boston, Massachusetts.  Assistant Professor of Anesthesiology anesthesiology (ăn'ĭsthē'zēŏl`əjē), branch of medicine concerned primarily with procedures for rendering patients insensitive to pain, and for supporting life systems under the strains of anesthesia and surgery. . Backed by leading venture capital firms Name Location Founding date Managing Partners/Directors Specialty Capital managed
5AM Ventures Menlo Park, CA; Waltham, MA 2002 John Diekman, PhD (managing partner), Scott Rocklage, PhD (managing partner), Andrew Schwab (managing partner) life sciences $200M [1]
, Flagship Ventures and Polaris Venture Partners, the company has licensed a large patent estate covering these technologies on a worldwide exclusive basis from MIT and Brigham and Women's Hospital Brigham and Women's Hospital (BWH) is a hospital in the Longwood Area of the Boston, Massachusetts neighborhood of Mission Hill. With Massachusetts General Hospital, it is one of the two founding members of Partners HealthCare.  - Harvard Medical School. For more information, please visit the company's web site at www.bindbio.com.
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Publication:Business Wire
Date:Oct 11, 2007
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