B vitamins beneficial in celiac disease.
Vitamin B supplementation reduces blood levels of homocysteine, an amino acid implicated in cardiovascular disease, among patients with celiac disease. * Celiac disease is a digestive disorder characterized by an abnormal immune response to gluten (a protein found in wheat) and poor absorption of nutrients. Malabsorption of B vitamins due to celiac disease often results in elevated homocysteine.
The study included 25 adults with celiac disease who took daily B-vitamin supplements, 26 adults with celiac disease not taking vitamins, and 50 healthy controls who were not taking vitamins. Blood samples were drawn to measure vitamin B6, folate, vitamin B12, and homocysteine. Patients with celiac disease who took vitamins had significantly higher B-vitamin levels and significantly lower homocysteine levels compared with the other two groups.
The authors concluded that "regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management."
* World J Gastroenterol. 2009 Feb 28;15(8):955-60.
--Laura J. Ninger, ELS