Average wholesale price increase, top 10 Rx brands.

Average Wholesale Price
Increase, Top 10 Rx Brands
2008 vs. 2007

                Avg.
              Increase               Prescribed
Drug ([R])      (%)                         Use

Lunesta          19             Sleep disorders
Ambien CR        17             Sleep disorders
Celebrex         11             Pain, arthritis
Lyrica           10                  Nerve pain
Ultram ER        10                        Pain
Cymbalta          8      Nerve pain, depression
Skelaxin          7             Muscle relaxant
Nexium            7           Acid reflux, GERD
Oxycontin *       6                        Pain
Lidoderm          3               Shingles pain

* Top name-brand prescription drug in terms of
cost to plan: 6.8% of Rx expenses.

Sources: PMSI 2009 Annual Drug Trends Report;
WebMD