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Aurora Announces Issuance of U.S. Patent for Improved Green Fluorescent Proteins, GFP.


LA JOLLA, Calif.--(BW HealthWire)--June 4, 1997--Aurora Biosciences Corporation today announced the issuance of U.S. Patent Number 5,625,048 that relates to variants of Green Fluorescent Protein "EGFP" redirects here. EGFP may also refer to the ICAO airport code for Pembrey Airport.

The green fluorescent protein (GFP) is a protein, comprised of 238 amino acids (26,9 kDa), from the jellyfish Aequorea victoria
 (GFP) having increased brightness and distinct colors (wavelengths of emitted light).

The Company believes that these improved fluorescent proteins are valuable molecular tools for scientific research and drug discovery. The patented GFP technology is part of a portfolio of fluorescent technologies accessed by Bristol-Myers Squibb and Eli Lilly and Company Eli Lilly and Company (NYSE: LLY) is a global pharmaceutical company and one of the world's largest corporations. Eli Lilly's global headquarters is located in Indianapolis, Indiana, in the United States.  for functional genomics and high throughput screening as part of Aurora's Ultra-High Throughput Screening (UHTS) System syndicate.

"Issuance of the GFP patent is an indication of Aurora's screen technology leadership," said Doug Richards, Associate Director, Biotechnology Licensing, Bristol-Myers Squibb. "We believe that Aurora's fluorescent screening technologies will play an important role in how companies discover new medicines and analyze the wealth of potential targets from genomics."

Randy Riggs, Corporate Business Development, Eli Lilly and Company, added "Aurora's patented GFP technology will complement the state-of-the-art screening techniques used for drug discovery at our Sphinx subsidiary."

This patent recently issued from a series of patent applications exclusively licensed to Aurora by the Regents of the University of California The Regents of the University of California make up the governing board of the University of California. The Board has 26 full (i.e., voting) members:
  • The majority (18 Regents) are appointed by the Governor of California for 12-year terms.
. These technologies were first developed in the laboratory of one of the Company's scientific founders, Dr. Roger Y. Tsien Roger Yonchien Tsien (1952-) is an American chemist and a professor at the Department of Chemistry and Biochemistry, University of California, San Diego.[1] Birth and education
Roger Y. Tsien was born in New York, in 1952.
, a Howard Hughes Medical Institute Howard Hughes Medical Institute, (HHMI), nonprofit medical research organization founded in 1953 by Howard Hughes and largly funded from proceeds of the 1984–85 sale of Hughes Aircraft. Headquartered in Chevy Chase, Md.  Investigator and a Professor of Pharmacology, Chemistry, and Biochemistry at the University of California The University of California has a combined student body of more than 191,000 students, over 1,340,000 living alumni, and a combined systemwide and campus endowment of just over $7.3 billion (8th largest in the United States).  San Diego.

Aurora's UHTS system will include instrumentation being developed in a technology alliance with the Packard Instrument Company. As part of this alliance, Packard has an exclusive sublicense to sell to non-profit organizations for internal, non-commercial research these patented GFPs.

Aurora designs and develops proprietary drug discovery systems, services and technologies to accelerate and enhance the discovery of new medicines. Aurora is developing an integrated technology platform comprised of a portfolio of proprietary fluorescent assay technologies and an ultra-high throughput screening system designed to allow assay miniaturization min·i·a·tur·ize  
tr.v. min·i·a·tur·ized, min·i·a·tur·iz·ing, min·i·a·tur·iz·es
To plan or make on a greatly reduced scale.



min
.

CONTACT: Aurora Biosciences

Paul A. Grayson, 619/452-5000
COPYRIGHT 1997 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1997, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Date:Jun 4, 1997
Words:330
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