Auriga Laboratories Acquires Exclusive Rights to Patent-Protected Product with Proven Results in the Treatment of the Common Cold.Two Randomized ran·dom·ize tr.v. ran·dom·ized, ran·dom·iz·ing, ran·dom·iz·es To make random in arrangement, especially in order to control the variables in an experiment. , Double-Blind, Placebo-Controlled Clinical Trials Results Show Significant Reduction in Length of and Symptoms Related to the Common Cold NORCROSS, Ga. -- Auriga Laboratories, Inc. (OTCBB OTCBB See OTC Bulletin Board (OTCBB). : ARGA ARGA Arkansas Rice Growers Association (North Little Rock, AR) ) or "Auriga", a specialty pharmaceutical company with products for the treatment of acute respiratory diseases, dermatological dermatological, dermatologic pertaining to dermatology; of or affecting the skin. conditions, and Xerostomia xerostomia /xe·ro·sto·mia/ (zer?o-sto´me-ah) dryness of the mouth due to salivary gland dysfunction. xe·ro·sto·mi·a n. , announced today that it has entered into an exclusive license to make, use and sell proprietary products, technology and patents relating to relating to relate prep → concernant relating to relate prep → bezüglich +gen, mit Bezug auf +acc the treatment of the common cold with zinc. The first product, ColdCure zinc lozenges, employ a novel formulation to dramatically reduce the duration and severity of common cold symptoms in two independent, randomized, double-blind, placebo-controlled clinical trials published in peer reviewed medical journals. This unique formulation is protected by nine patents. The most recent clinical study1 involved 48 participants (25 in the Zinc group and 23 in the placebo group). Compared with the placebo group, the zinc group had shorter mean overall duration of cold symptoms (4.5 vs. 8.1 days), along with reductions in cough and nasal discharge and decreased total severity scores for all symptoms (P<0.002, test for treatment times time interaction). The study concluded that, "The results supported the conclusion that administration of zinc lozenges was associated with reduced duration and severity of cold symptoms, especially cough. Improvement in clinical symptoms with zinc treatment may be related to a decrease in proinflammatory cytokine Cytokine Any of a group of soluble proteins that are released by a cell to send messages which are delivered to the same cell (autocrine), an adjacent cell (paracrine), or a distant cell (endocrine). levels." Numerous zinc products are available; however, the ColdCure zinc lozenge lozenge /loz·enge/ (loz´enj) [Fr.] 1. troche; a discoid-shaped, solid, medicinal preparation for solution in the mouth, consisting of an active ingredient incorporated in a suitably flavored base. 2. , through its patented formulation, has the highest level of zinc ion availability (ZIA ZIA Zia International Airport (DAC) ZIA Zero-Interaction Authentication ZIA Zero-Power Interconnect Array ZIA Zinc Ion Availability ZIA Zone Immunoassay ZIA Zentrale Intelligence Agentur (German) ). A zinc product having a strong ZIA value will release hydrated hy·drat·ed adj. Chemically combined with water, especially existing in the form of a hydrate. Adj. 1. hydrated - containing combined water (especially water of crystallization as in a hydrate) hydrous zinc ions (Zn2+) at physiologic pH evidenced by oral drying (astringency astringency /astrin·gen·cy/ (ah-strin´jen-se) the quality of being astringent. ) and major reduction in duration of colds. Zinc lozenges having a ZIA value of 100 are strong enough to terminate incipient incipient (insip´ēent), adj beginning, initial, commencing. incipient beginning to exist; coming into existence. colds in less than a day or reduce the average duration of existing colds by a week. "We are excited to have acquired the rights to market this revolutionary product," said Philip S. Pesin, Chief Executive Officer of Auriga. "While there are many products on the market today that claim to reduce symptoms associated with and duration of the common cold, we believe the data and formulation science supporting ColdCure is quite compelling. Auriga's ability to offer clinically-proven zinc therapy for treatment and termination of colds via ColdCure along with our respiratory franchises, Extendryl[R] and Levall[R], means turnkey treatment to our patients suffering from cold symptoms. While ColdCure has previously only been available via limited distribution, we feel that by marketing the product through our sales force and other channels that this product has the potential to become a blockbuster over-the-counter solution to one of the most common and widespread medical problems." Most cold-related lozenges currently available have a zero or low ZIA value, suggesting that they do not release zinc ions and are not astringent astringent (əstrĭn`jənt), substance that shrinks body tissues. Astringent medicines cause shrinkage of mucous membranes or exposed tissues and are often used internally to check discharge of serum or mucous secretions in sore throat, . It is the lozenge ZIA value in addition to the appropriate amount of zinc contained within the lozenge, which results in duration changes in cold. Typically, non-astringent lozenges are found in stores, resulting in a limited effect on colds. 1Prasad Prasāda (Sanskrit: प्रसाद), prasād/prashad (Hindi), Prasāda in (Kannada), prasādam (Tamil), or prasadam et al., "Duration of Symptoms and Plasma Cytokine Levels in Patients with the Common Cold Treated with Zinc Acetate <noinclude> </noinclude> <noinclude> </noinclude> Zinc acetate is the chemical compound with the formula Zn(O2CCH3)2 but more commonly refers to the dihydrate Zn(O2CCH3)2(H2O) ." Annals of Internal Medicine Annals of Internal Medicine (Ann Intern Med) is an academic medical journal published by the American College of Physicians (ACP). It publishes research articles and reviews in the area of internal medicine. Its current editor is Harold C. Sox. . 2000. pp. 245-252. About Auriga Laboratories(TM) Auriga Laboratories(TM) is a specialty pharmaceutical company capitalizing on high-revenue markets and opportunities in the pharmaceutical industry through proactive sales, integrated marketing and advanced in-house drug development capabilities. The Company's high-growth business model combines acquisition of proven brand names, powerful product development strategies and rapidly-growing national sales teams and marketing operations. Auriga acquires valuable brand portfolios that are no longer a strategic focus for large pharmaceutical companies, then capitalizes on untapped marketplace opportunities through brand extension and directed sales/marketing programs. The Company's drug-development pipeline leverages novel material science and advanced drug delivery technologies to produce improved formulations of successful brands to further expand markets, sales and clinical indications for proven, successful products. Auriga's exclusive prescription product portfolio currently includes Aquoral(TM) for the treatment of Xerostomia, Akurza(TM) and Xyralid(TM) dermatology products, and the Extendryl[R] and Levall[R] families of products for relief of symptoms associated with a range of acute respiratory diseases. Auriga plans to become a fully integrated pharmaceutical company by acquiring its own manufacturing and development capabilities. Moving forward, the Company will seek to acquire and/or in-license additional products and technologies to further grow revenues. For more information, please visit: www.aurigalabs.com. Forward-Looking Statements: The information contained herein includes forward-looking statements. These statements relate to future events or to the Company's future financial performance, and involve known and unknown risks, uncertainties and other factors that may cause its actual results, levels of activity, performance or achievements to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. Any forward-looking statement reflects the Company's current views with respect to future events and is subject to these and other risks, uncertainties and assumptions relating to its operations, results of operations, growth strategy and liquidity. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. Important factors that could cause actual results to differ materially from the Company's expectations include, but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the Company from time to time with the United States United States, officially United States of America, republic (2005 est. pop. 295,734,000), 3,539,227 sq mi (9,166,598 sq km), North America. The United States is the world's third largest country in population and the fourth largest country in area. Securities and Exchange Commission and other regulatory authorities. Statements regarding the Company's ability to increase its sales force and the success of such sales force in selling its products in light of competitive and other factors, the regulatory status and/or regulatory compliance of its products, the Company's ability to secure additional financing, its ability to sustain market acceptance for its products, its dependence on collaborators, the Company's ability to find and execute strategic transactions, its potential exposure to litigation An action brought in court to enforce a particular right. The act or process of bringing a lawsuit in and of itself; a judicial contest; any dispute. When a person begins a civil lawsuit, the person enters into a process called litigation. , the Company's exposure to product liability claims, and the Company's prices, future revenues and income and cash flows and other statements that are not historical facts contain predictions, estimates and other forward-looking statements. Although the Company believes that its expectations are based on reasonable assumptions, it can give no assurance that its goals will be achieved and these statements will prove to be accurate. Important factors could cause actual results to differ materially from those included in the forward-looking statements. |
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